Henri Jean Pascal Gastaut (April 15, 1915,
Monaco
Monaco (; ), officially the Principality of Monaco (french: Principauté de Monaco; Ligurian: ; oc, Principat de Mónegue), is a sovereign city-state and microstate on the French Riviera a few kilometres west of the Italian region of Lig ...
– July 14, 1995
Marseille
Marseille ( , , ; also spelled in English as Marseilles; oc, Marselha ) is the prefecture of the French department of Bouches-du-Rhône and capital of the Provence-Alpes-Côte d'Azur region. Situated in the camargue region of southern Franc ...
) was a French
neurologist
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...
and
epileptologist An epileptologist is a neurologist who specializes in the treatment of epilepsy. Epileptologists are experts in epileptic seizures and seizure disorders, anticonvulsants, and special situations involving seizures, such as cases in which all treatme ...
.
Biography
Gastaut was educated in medicine at the
University of Marseille
Aix-Marseille University (AMU; french: Aix-Marseille Université; formally incorporated as ''Université d'Aix-Marseille'') is a public research university located in the Provence region of southern France. It was founded in 1409 when Louis II o ...
, obtaining his medical doctorate in 1945. Thereafter he trained in
neurology
Neurology (from el, wikt:νεῦρον, νεῦρον (neûron), "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine), medicine dealing with the diagnosis and treatment of all categories of co ...
with Henri Roger and in
neuroanatomy
Neuroanatomy is the study of the structure and organization of the nervous system. In contrast to animals with radial symmetry, whose nervous system consists of a distributed network of cells, animals with bilateral symmetry have segregated, defin ...
with Lucien Cornil in Marseille. In 1953 he became head of the neurobiological laboratories at the Marseille Hospital. In 1954 he succeeded Cornil as professor of
anatomical pathology
Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination ...
and in 1960 he was appointed as director of the regional centre for epileptic children.
[Biography of Henri Jean Pascal Gastaut]
at Who Named It
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograph ...
In 1973 a chair of clinical
neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated b ...
was created for him,
[ ILAE.org]
In Memoriam Henri Gastaut 1915-1995 a
tenure
Tenure is a category of academic appointment existing in some countries. A tenured post is an indefinite academic appointment that can be terminated only for cause or under extraordinary circumstances, such as financial exigency or program disco ...
he held until his retirement in 1984.
His major interests involved research of
electroencephalography
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex ...
and brain functionality in
epilepsy
Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ...
. In 1957 he described the
hemiconvulsion-hemiplegia-epilepsy(HHE) syndrome, in 1961 and 1966 the Lennox-Gastaut syndrome, and in 1981 and 1982 the late variant of the benign childhood epilepsy with occipital paroxysms.
After the
second world war
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
he was influential in reactivating the
International League Against Epilepsy The International League Against Epilepsy was started in 1909. Its goal is to improve the lives of people with epilepsy through research.
They run the medical journals ''Epilepsia'', ''Epilepsia Open'', and ''Epileptic Disorders
''Epileptic Disor ...
(ILAE). After serving as
president elect from 1953 to 1957, he was secretary general from 1957 to 1969 of the ILAE, before being elected as its president from 1969 to 1973 and being past president from 1973 to 1977. In addition he was Chairman of the Commission on Terminology of the ILAE in 1963 which resulted in the publication of a Dictionary of Epilepsy.
He attempted to understand possible ties between epilepsy and artistic genius in individuals such as
Fedor Dostoyevski,
Gustave Flaubert
Gustave Flaubert ( , , ; 12 December 1821 – 8 May 1880) was a French novelist. Highly influential, he has been considered the leading exponent of literary realism in his country. According to the literary theorist Kornelije Kvas, "in Flauber ...
, and
Vincent van Gogh
Vincent Willem van Gogh (; 30 March 185329 July 1890) was a Dutch Post-Impressionism, Post-Impressionist painter who posthumously became one of the most famous and influential figures in Western art history. In a decade, he created about 2 ...
, and published a number of papers about this relationship.
[
In 1967 he was elected dean of the University of Marseille School of Medicine.][
]
Awards
Among others, Gastaut was awarded as "Ambassador for Epilepsy" by the ILAE and International Bureau for Epilepsy The International Bureau for Epilepsy is a non-for-profit started in 1961. Its members are from both the lay public and a professional background. It is global in scope. The organization often collaborates with the International League Against Epile ...
in 1968 and with the Lennox Award of the American Epilepsy Society (AES) in 1977.
Published works
* Gastaut H. The Epilepsies. Electro-Clinical Correlations. Springfield, Illinois, C. C. Thomas 1954
* Gastaut H, Vigouroux M, eds. Documents Selectionnés parmi 500 Auteurs et Présentés au Colloque Internationale Béthesda sur l’Épilepsie du Lobe Temporal. Marseilles, M. Leconte 1957
* Fischgold H, Gastaut H, eds. Conditionnement et Réactivité en Electroencéphalographie (Colloque de Marseille, 1955). Supplement to Electroencephalography and Clinical Neurophysiology. Paris, Masson & Cie 1957
* Gastaut H, Gastaut Y. La Syncope Vaso-Vagale Réflexe. Sa Différenciation d’Avec l’Épilepsie. Son Traitement. without place, Editions Sandoz ohne Jahr (1958)
* Fischgold H, Gastaut H, eds. Rayons X. Radio-Isotopes et E.E.G. dans l’Épilepsie (Colloque de Marseille, 1958). Supplement 17 to Electroencephalography and Clinical Neurophysiology. Paris, Masson & Cie 1960
* Gastaut H, Meyer JS, eds. Anoxia and the Electroencephalogram. Springfield, Illinois, C. C. Thomas 1961
* Bonduelle M, Gastaut H, eds. Les Myoclonies. Rapports présentés la XXVIIIe Réunion Neurologique Internationale, Paris, 4 – 5 Juin, 1968. Paris, Masson & Cie 1963
* Gastaut H, Roger J, Soulayrol R, Pinsard N, eds. L‘Encéphalopathie Myoclonique Infantile avec Hypsarythmie (Syndrome de West). Compte Rendu de la Réunion Européenne d’Information Electroencéphalographique (9e Colloque de Marseille, 1960). Paris, Masson & Cie 1964
* Gastaut H, Roger J, Lob H, eds. Les États de Mal Épileptiques. Compte Rendu de la Réunion Européenne d’Information Électroencéphalographique (Xe Colloque de Marseille, 1962). Électroencéphalographie et Neurophysiologie Clinique, Nouvelle Série (Vol 3). Paris, Masson & Cie 1967
* Gastaut H, Jasper H, Bancaud J, Waltregny A, eds. The Physiopathogenesis of the Epilepsies. Springfield, Illinois, C. C. Thomas 1969
* Gastaut H, Broughton R. Epileptic Seizures. Clinical and Electrographic Features, Diagnosis and Treatment. Springfield, Illinois, C. C. Thomas 1972
* Gastaut H en collaboration avec un groupe international d’experts. Dictionnaire De LʼÉpilepsie. Partie I: Définitions. Organisation Mondiale de la Santé, Genève 1973; English edition: Gastaut H in Collaboration with an International Group of Experts. Dictionary of Epilepsy. Part I: Definitions. World Health Organization, Geneva 1973; German edition: Gastaut H, unter Mitarbeit einer internationalen Expertengruppe (Kugler J, Übersetzer). Wörterbuch der Epilepsie. Stuttgart, Hippokrates 1976
* Gastaut H, Tassinari CA, eds. Epilepsies. Handbook of Electroencephalography and Clinical Neurophysiology, Vol 13a. Clinical EEG, III. Part A. Amsterdam, Elsevier 1975
* Beaumanoir A, Gastaut H, Naquet R, eds. Reflex Seizures and Reflex Epilepsies. International Symposium on Reflex Seizures and Reflex Epilepsies, Genève, Juin 1988. Genève, Editions Médicine et Hygiene 1989
Associated eponyms
* '' Gastaut's syndrome'': Photosensitive epilepsy
Photosensitive epilepsy (PSE) is a form of epilepsy in which seizures are triggered by visual stimuli that form patterns in time or space, such as flashing lights; bold, regular patterns; or regular moving patterns.
PSE affects approximately o ...
with heliotropism
Heliotropism, a form of tropism, is the diurnal or seasonal motion of plant parts (flowers or leaves) in response to the direction of the Sun.
The habit of some plants to move in the direction of the Sun, a form of tropism, was already known by t ...
and arm rocking.
* '' Lennox-Gastaut syndrome'': An epileptic condition with onset in childhood with nighttime myoclonic seizure
Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle or a group of muscles, different from clonus, which is rhythmic or regular. Myoclonus (myo "muscle", clonic "jerk") describes a medical sign and, generally, is ...
s, head nodding, and drop attack A drop attack is a sudden fall without loss of consciousness. Drop attacks stem from diverse mechanisms, including orthopedic causes (for example, leg weakness and knee instability), hemodynamic causes (for example, transient vertebrobasilar insuf ...
s especially prominent.Genetics Home References
Lennox-Gastaut syndrome
References
{{DEFAULTSORT:Gastaut, Henri
Electroencephalographers
French neuroscientists
Academic staff of Aix-Marseille University
1915 births
1995 deaths
20th-century French physicians
French epileptologists