Hemslecin is any of several compounds obtained from plants of the genus ''

Hemsleya ''Hemsleya'' is a genus of flowering plants belonging to the family Cucurbitaceae. Its native range is Eastern Himalayas to southern China and Papuasia. It is native to the countries of Assam (in India), Bismarck Archipelago (island group, part ...

'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to

cucurbitacin F Cucurbitacin is a class of biochemical compounds that some plants – notably members of the pumpkin and gourd family, Cucurbitaceae – produce and which function as a defence against herbivores. Cucurbitacins are chemically classified as t ...

.Jian-Chao Chen, Gao-Hong Zhang, Zhong-Quan Zhang, Ming-Hua Qiu, Yong-Tang Zheng, Liu-Meng Yang, Kai-Bei Yu (2008), "Octanorcucurbitane and Cucurbitane Triterpenoids from the Tubers of ''Hemsleya endecaphylla'' with HIV-1 Inhibitory Activity". ''J. Nat. Prod.'' volume 71, pages 153–155 Jian Chao Chen, Ming Hua Chiu, Rui Lin Nie, Geoffrey A. Cordell and Samuel X. Qiu (2005), "Cucurbitacins and cucurbitane glycosides: structures and biological activities" ''Natural Product Reports'', volume 22, pages 386-399 The hemslecins include: *

Hemslecin A Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin, cucurbitacin F.Jian-C ...

, 25-acetoxy-23,24-dihydrocucurbitacin F, from '' Hemsleya endecaphylla'' and from '' Helmseya amabilis'' *

Hemslecin B Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin, cucurbitacin F.Jian-C ...

, 23,24-dihydrocucurbitacin F, from ''Hemsleya endecaphylla'' *

Hemslecin C Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin, cucurbitacin F.Jian-C ...

, synthesized from hemslecin A *

Hemslecin D Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin, cucurbitacin F.Jian-C ...

from ''Helmseya lijiangensis'' *

Hemslecin E Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin F.Jian-Chao Chen, Gao- ...

from ''Helmseya lijiangensis'' *

Hemslecin F Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin F.Jian-Chao Chen, Gao- ...

from ''Helmseya lijiangensis'' *

Hemslecin G Hemslecin is any of several compounds obtained from plants of the genus ''Hemsleya'', which are used in Asian folk medicine. They are triterpene derivatives, specifically with the cucurbitane skeleton, related to cucurbitacin F.Jian-Chao Chen, Gao- ...

from ''Helmseya gigantha'' Hemslecins A and B have antibacterial properties, and have been proven to be effective against infectious diseases such as enteritis, bronchitis, acute tonsillitis, and bacillary dysentery.

References

{{Chemistry index Triterpenes