Hemoglobin H disease is a type of
alpha thalassemia
Alpha-thalassemia (α-thalassemia, α-thalassaemia) is a form of thalassemia involving the genes ''HBA1'' and ''HBA2''. Thalassemias are a group of inherited blood conditions which result in the impaired production of hemoglobin, the molecule t ...
caused by impaired production of three of the four alpha globins, coded by genes
HBA1
Hemoglobin subunit alpha, Hemoglobin, alpha 1, is a hemoglobin protein that in humans is encoded by the ''HBA1'' gene.
Gene
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseu ...
and
HBA2
Hemoglobin, alpha 2 also known as HBA2 is a gene that in humans codes for the alpha globin chain of hemoglobin.
Function
The human alpha globin gene cluster is located on chromosome 16 and spans about 30 kb, including seven alpha like globin ...
.
See also
*
Hemoglobin Barts Hemoglobin Barts, abbreviated Hb Barts, is an abnormal type of hemoglobin that consists of four gamma globins. It is moderately insoluble, and therefore accumulates in the red blood cells. Hb Barts has an extremely high affinity for oxygen, so it ...
References
External links
Blood disorders
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