Helen Blackwell
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Helen E. Blackwell (born 1972) is an American organic chemist and chemical biologist. She is a professor at the
University of Wisconsin–Madison A university () is an educational institution, institution of higher education, higher (or Tertiary education, tertiary) education and research which awards academic degrees in several Discipline (academia), academic disciplines. Universities ty ...
.


Education

Blackwell is a native of Shaker Heights, Ohio and was educated as an undergraduate at
Oberlin College Oberlin College is a Private university, private Liberal arts colleges in the United States, liberal arts college and conservatory of music in Oberlin, Ohio. It is the oldest Mixed-sex education, coeducational liberal arts college in the United S ...
, receiving a Bachelor of Arts degree in chemistry in 1994. She received a Ph.D. in organic chemistry from the California Institute of Technology in 1999 working with
Robert Grubbs Robert Howard Grubbs ForMemRS (February 27, 1942 – December 19, 2021) was an American chemist and the Victor and Elizabeth Atkins Professor of Chemistry at the California Institute of Technology in Pasadena, California. He was a co-recipient o ...
.


Career and research

Nearing the end of her doctoral education in 1999, Blackwell gained an interest in biology and joined Stuart Schreiber's lab at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
. At the time, the lab was focusing on animal models, but Blackwell decided to work with plants. During her research, Blackwell identified several small-molecule sirtuin inhibitors in ''
Arabidopsis ''Arabidopsis'' (rockcress) is a genus in the family Brassicaceae. They are small flowering plants related to cabbage and mustard. This genus is of great interest since it contains thale cress (''Arabidopsis thaliana''), one of the model organi ...
'' plants. Blackwell's research utilizes
chemical probe In the field of chemical biology, a chemical probe is a small molecule that is used to study and manipulate a biological system such as a cell or an organism by reversibly binding to and altering the function of a biological target (most commonly ...
s—synthesized using solution-phase and solid-phase synthesis, and combinatorial chemistry—to better understand bacterial communication and interactions between a microbe and its host, more specifically, how plants and animals react to microbe invasion, and how bacteria use quorum sensing to determine when to attack their host. Blackwell is a fellow of the American Association for the Advancement of Science, and has received the
Agnes Fay Morgan Research Award The Agnes Fay Morgan Research Award was established in 1951 by the Iota Sigma Pi honorary society for women in chemistry. The award is given for research achievement in chemistry or biochemistry to a woman not over forty years of age at the tim ...
.


Publications

Blackwell has written more than 130 academic journal papers, she is the co-author of , , and


References

{{DEFAULTSORT:Blackwell, Helen Living people 21st-century American chemists University of Wisconsin–Madison faculty Oberlin College alumni California Institute of Technology alumni 1972 births Chemists from Ohio