Harry F. Noller (born June 10, 1939) is an American

biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...

, and since 1992 the director of the University of California, Santa Cruz's ''Center for the Molecular Biology of RNA''. He has made significant contributions to our understanding of the

ribosome Ribosomes ( ) are macromolecular machines, found within all cells, that perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to ...

and is a member of the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

Early life and education

Noller is a native of

Oakland, California Oakland is the largest city and the county seat of Alameda County, California, United States. A major West Coast of the United States, West Coast port, Oakland is the largest city in the East Bay region of the San Francisco Bay Area, the third ...

. He earned his B.S. degree in biochemistry at the

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...

in 1960 and his Ph.D. in chemistry from the

University of Oregon The University of Oregon (UO, U of O or Oregon) is a public research university in Eugene, Oregon. Founded in 1876, the institution is well known for its strong ties to the sports apparel and marketing firm Nike, Inc, and its co-founder, billion ...

in 1965 He carried out post-doctoral work at the Medical Research Council Laboratory of Molecular Biology in Cambridge and the Institute of Molecular Biology at the

University of Geneva The University of Geneva (French: ''Université de Genève'') is a public research university located in Geneva, Switzerland. It was founded in 1559 by John Calvin as a theological seminary. It remained focused on theology until the 17th centu ...

Scientific contributions and honors

Noller joined the faculty at University of California, Santa Cruz in 1968. In his decades-long study of the molecular translational machinery of the cell, he has made fundamental contributions in understanding the structure and function of the cell's protein-synthesis factory, the

. Notable amongst these contributions are having demonstrated that the ribosome is a

ribozyme Ribozymes (ribonucleic acid enzymes) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar to the action of protein enzymes. The 1982 discovery of ribozymes demonst ...

and leading the solution of the first

crystal structures A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macrosc ...

molecular A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...

resolution Resolution(s) may refer to: Common meanings * Resolution (debate), the statement which is debated in policy debate * Resolution (law), a written motion adopted by a deliberative body * New Year's resolution, a commitment that an individual mak ...

for complete ribosomes. Noller was elected to the

in 1992. He has been recognized with prizes from the Paul Ehrlich Foundation in 2006 and the

Gairdner Foundation The Gairdner Foundation is a non-profit organization devoted to the recognition of outstanding achievements in biomedical research worldwide. It was created in 1957 by James Arthur Gairdner to recognize and reward the achievements of medical resea ...

in 2007, each of which was shared with eventual winners of the

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

for 2009. He won a

Breakthrough Prize The Breakthrough Prizes are a set of international awards bestowed in three categories by the Breakthrough Prize Board in recognition of scientific advances. The awards are part of several "Breakthrough" initiatives founded and funded by Yuri Mi ...

in 2016.

References

External links

Harry Noller faculty description page from UCSC MCDB Department
{{DEFAULTSORT:Noller, Harry F. 1939 births American biochemists American biophysicists Living people Members of the United States National Academy of Sciences Foreign Members of the Russian Academy of Sciences University of California, Berkeley alumni University of California, Santa Cruz faculty University of Oregon alumni