Harry Melvin Rose (May 30, 1906, in

Niles, Ohio Niles is a city in southern Trumbull County, Ohio, United States, situated at the confluence of the Mahoning River and Mosquito Creek. The city's population was 18,443 at the 2020 census. It is a suburb of the Youngstown–Warren metropolitan a ...

– November 4, 1986, in

Meredith, New Hampshire Meredith is a town in Belknap County, New Hampshire, United States. The population was 6,662 at the 2020 census. Meredith is situated in the state's Lakes Region and serves as a major resort town. Meredith Village, the commercial center of the t ...

) was an American physician and microbiologist whose laboratory at Columbia University developed an accurate diagnostic test for

rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are invol ...

in 1948.Obituary in the NY Times of November 7, 1986
/ref> The test became known as the Rose-Waaler or Waaler-Rose test, since it was independently developed by both Rose and the Norwegian bacteriologist Erik Waaler. Rose was among the first recipients of the

Gairdner Foundation International Award The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a ...

for his work in developing the test.Gairdner Foundation International page on Harry M. Rose
/ref> Rose attended

Yale University Yale University is a Private university, private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the List of Colonial Colleges, third-oldest institution of higher education in the United Sta ...

, then went to medical school at

Cornell University Medical College The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with New ...

, receiving his medical degree in 1932. He came to

New York Presbyterian Hospital The NewYork-Presbyterian Hospital is a nonprofit academic medical center in New York City affiliated with two Ivy League medical schools, Cornell University and Columbia University. The hospital comprises seven distinct campuses located in the New ...

as an intern in 1938 and received a faculty appointment at the College of Physicians and Surgeons in 1940 as an assistant in medicine, assigned to Department of

Bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...

. With the outbreak of

World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing ...

, Rose served on the Armed Forces

Epidemiological Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...

Board and performed research on

tropical disease Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by for ...

s for the United States government. In 1952, Rose was appointed John E. Borne Professor and chair of the Department of Bacteriology at

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

. He changed the name to the Department of Microbiology to better reflect the ongoing research in the department. In addition to his research on rheumatoid arthritis, Rose studied antibiotic mechanisms and

virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsk ...

es and contributed to influenza vaccine development. He served as

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ...

of the ''

Journal of Immunology The ''Journal of Immunology'' is a biweekly peer-reviewed medical journal that publishes basic and clinical studies in all aspects of immunology. Established in 1916, it changed its name to ''Journal of Immunology, Virus Research and Experimental C ...

'' and was appointed a fellow of the

American College of Physicians The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...

and the

American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's sta ...

. He was elected a member of the National Academy of Sciences. Rose retired from Columbia University in 1973 and moved to

Sandwich, New Hampshire Sandwich is a town in Carroll County, New Hampshire, United States. Its population was 1,466 at the 2020 census. Sandwich includes the villages of Center Sandwich and North Sandwich. Part of the White Mountain National Forest is in the north, a ...

, where he recertified as a diplomate in internal medicine and continued to practice medicine until 1984.

References

Columbia University faculty Members of the United States National Academy of Sciences People from Niles, Ohio American microbiologists 1906 births 1986 deaths People from Sandwich, New Hampshire Weill Cornell Medical College alumni {{US-med-bio-stub