Haplogroup L7 (mtDNA)
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Haplogroup L4 is a
human mitochondrial DNA Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondri ...
(mtDNA) haplogroup. It is a small maternal clade primarily restricted to Africa. L4 is important in
East Africa East Africa, Eastern Africa, or East of Africa, is the eastern subregion of the African continent. In the United Nations Statistics Division scheme of geographic regions, 10-11-(16*) territories make up Eastern Africa: Due to the historical ...
. The highest frequencies are in
Tanzania Tanzania (; ), officially the United Republic of Tanzania ( sw, Jamhuri ya Muungano wa Tanzania), is a country in East Africa within the African Great Lakes region. It borders Uganda to the north; Kenya to the northeast; Comoro Islands and ...
among the Hadza at 60-83% and Sandawe at 48%. It has two branches, L4a and L4b. Subgroup L4a was formerly called L7 and considered a separate subclade of L3'4'7. It has been recognized as a subclade of L4, with L3 as its outgroup by Behar et al. (2008). The parent clade L3'4 is to have emerged at 106–66 kya. L4 is not much later than this, estimated at 87 kya by Fernandes et al. (2015).Fernandes V, Triska P, Pereira JB, Alshamali F, Rito T, Machado A, et al. (2015) Genetic Stratigraphy of Key Demographic Events in Arabia. PLoS ONE 10(3): e0118625.


Phylogeny

The following phylogeny is based on van Oven and Kayser (2008). * L3'4 **L4 *** L4a (formerly known as L7), mutations: 195C, 3357, 5460, 10373, 11253, 11344, 11485, 12414, 13174, 14302, 16260. ****L4a1 *****L4a1a ****L4a2 ***L4b, mutations: 709, 3918. ****L4b1 ****L4b2 (formerly known as L3g or L4g) *****L4b2a ******L4b2a1 ******L4b2a2 *******L4b2a2a *******L4b2a2b *****L4b2b


References


External links

*Ian Logan'
Mitochondrial DNA Site
*Mannis van Oven'
Phylotree
L4 {{genetics-stub