Hans Chiari (4 September 1851 − 6 May 1916) was an

Austria Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous ...

pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...

, who was a native of

Vienna en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST ...

. He was the son of

gynecologist Gynaecology or gynecology (see spelling differences) is the area of medicine that involves the treatment of women's diseases, especially those of the reproductive organs. It is often paired with the field of obstetrics, forming the combined ...

Johann Baptist Chiari (1817–1854), and brother to rhinolaryngologist

Ottokar Chiari Ottokar Chiari (1 February 1853 – 12 May 1918) was an Austrian laryngologist and professor at the University of Vienna who was a native of Prague. At Vienna he was an assistant to Leopold von Schrötter (1837–1908), and later succeeded Ka ...

(1853–1918).

Biography

Chiari studied medicine in Vienna, where he was an assistant to Karl Freiherr von Rokitansky (1804–1878) and Richard Ladislaus Heschl (1824–1881). In 1878 he received his habilitation in

pathological anatomy Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination o ...

, and within a few years became an associate professor at the University of Prague. At

Prague Prague ( ; cs, Praha ; german: Prag, ; la, Praga) is the capital and List of cities in the Czech Republic, largest city in the Czech Republic, and the historical capital of Bohemia. On the Vltava river, Prague is home to about 1.3 milli ...

he was also superintendent of the pathological-anatomical museum. In 1906 he relocated to the

University of Strasbourg The University of Strasbourg (french: Université de Strasbourg, Unistra) is a public research university located in Strasbourg, Alsace, France, with over 52,000 students and 3,300 researchers. The French university traces its history to the ea ...

as a professor of pathological anatomy. Chiari's research dealt largely with postmortem examinations, and most of his numerous writings are the result of

autopsies An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any d ...

. In the 1890s he described a condition involving deformities of the cerebellum, and brainstem in children with herniation of the

spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the sp ...

.Arnold–Chiari malformation
@

Who Named It ''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliograp ...

The phenomenon was later to become known as the "

Arnold–Chiari malformation Chiari malformation (CM) is a structural defect in the cerebellum, characterized by a downward displacement of one or both cerebellar tonsils through the foramen magnum (the opening at the base of the skull). CMs can cause headaches, difficu ...

", named after Chiari and German pathologist,

Julius Arnold Julius Arnold (19 August 1835 – 3 February 1915) was a German pathologist born in Zurich. He was the son of anatomist Friedrich Arnold (1803–1890). He studied medicine at the Universities of Heidelberg, Prague, Vienna and Berlin, where he wa ...

(1835–1915). The malformation was given its name in 1907 by two of Dr. Arnold's students. Another medical term named after Chiari is the

Budd–Chiari syndrome Budd–Chiari syndrome is a very rare condition, affecting one in a million adults. The condition is caused by occlusion of the hepatic veins that drain the liver. It presents with the classical triad of abdominal pain, ascites, and liver enlarge ...

, which is

ascites Ascites is the abnormal build-up of fluid in the abdomen. Technically, it is more than 25 ml of fluid in the peritoneal cavity, although volumes greater than one liter may occur. Symptoms may include increased abdominal size, increased weight, a ...

and

cirrhosis Cirrhosis, also known as liver cirrhosis or hepatic cirrhosis, and end-stage liver disease, is the impaired liver function caused by the formation of scar tissue known as fibrosis due to damage caused by liver disease. Damage causes tissue rep ...

of the

liver The liver is a major organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it ...

caused by an obstruction of the

hepatic veins In human anatomy, the hepatic veins are the veins that drain venous blood from the liver into the inferior vena cava (as opposed to the hepatic portal vein which conveys blood from the gastrointestinal organs to the liver). There are usually thre ...

due to a blood clot. It is named in conjunction with British physician George Budd (1808–1882). Lastly, Chiari is also famous for describing the "Chiari network", an embryonic remnant found in the

right atrium The atrium ( la, ātrium, , entry hall) is one of two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two at ...

, first published in 1897.

Publications

* "Über Veränderungen des Kleinhirns infolge von Hydrocephalie des Grosshirns", ''Deutsche medicinische Wochenschrift'', Berlin, 1891, 17: 1172–1175 – On cerebellar changes caused by

hydrocephalus Hydrocephalus is a condition in which an accumulation of cerebrospinal fluid (CSF) occurs within the brain. This typically causes increased pressure inside the skull. Older people may have headaches, double vision, poor balance, urinary inc ...

of the

cerebrum The cerebrum, telencephalon or endbrain is the largest part of the brain containing the cerebral cortex (of the two cerebral hemispheres), as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb ...

. * "Über Veränderungen des Kleinhirns, der Pons und der Medulla oblongata, infolge von congenitaler Hydrocephalie des Grosshirns", ''Denkschriften der Akademie der Wissenschaften in Wien'', 1895, 63: 71. – On changes to the cerebellum,

pons The pons (from Latin , "bridge") is part of the brainstem that in humans and other bipeds lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of Va ...

and the medulla oblongata, caused by hydrocephalus of the cerebrum.

References

* * * * * * *

External links

* Weill Cornell Chiari CARE http://weillcornellbrainandspine.org/chiari * The Chiari Institute https://web.archive.org/web/20080505070336/http://chiariinstitute.com/ * The Chiari Center of Wisconsin http://www.wichiaricenter.org/
Hans Chiari
@

{{DEFAULTSORT:Chiari, Hans Austrian pathologists 1851 births 1916 deaths Physicians from Vienna University of Strasbourg faculty

Biography

Publications

See also

References

External links