Global Network for Neglected Tropical Diseases
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The Global Network for Neglected Tropical Diseases is an advocacy initiative of the Sabin Vaccine Institute dedicated to raising the awareness, political will, and funding necessary to control and eliminate the most common Neglected Tropical Diseases (NTDs)—a group of disabling, disfiguring, and deadly diseases affecting more than 1.4 billion people worldwide living on less than $1.25 a day. The Global Network provides an advocacy platform for the broad NTD community that reaches the attention of policymakers, philanthropists, thought leaders, and the general public. Through that platform, the Global Network highlights the work—including implementation, research, advocacy, and policy efforts—of the NTD community at the local, national, and international levels. The Global Network collaborates closely with the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of ...
and other technical agencies, NGOs, donors, and the broader public health community; together they support international organizations, governments, and afflicted communities that work through regional strategies to advocate for and implement NTD control and elimination programs. __TOC__


History

At the September 2006
Clinton Global Initiative The Clinton Foundation (founded in 2001 as the William J. Clinton Presidential Foundation, and renamed in 2013 as the Bill, Hillary & Chelsea Clinton Foundation) is a nonprofit organization under section 501(c)(3) of the U.S. tax code. It was es ...
Annual Meeting, former U.S. President
Bill Clinton William Jefferson Clinton ( né Blythe III; born August 19, 1946) is an American politician who served as the 42nd president of the United States from 1993 to 2001. He previously served as governor of Arkansas from 1979 to 1981 and agai ...
announced the launch of The Global Network for Neglected Tropical Diseases—the first-ever global effort to combat NTDs in an integrated framework. At the time, NTD control was seen as a monumental task, with 1.4 billion people infected with and suffering from NTDs around the world. Over the last decade, several organizations on the ground had made significant progress on individual diseases, but reaching more people in need of treatment in a cost-effective way required an integrated approach to combating NTDs collectively. In the years since the Global Network launched, it has experienced significant growth as it deepens its commitment to fighting NTDs around the world through resource mobilization and advocacy efforts. Simultaneously, through the work of Global Network collaborators, hundreds of millions of the world’s poorest people are currently receiving a low-cost rapid-impact package of essential NTD drugs, enabling them to break out of a devastating
cycle of poverty In economics, a cycle of poverty or poverty trap is caused by self-reinforcing mechanisms that cause poverty, once it exists, to persist unless there is outside intervention. It can persist across generations, and when applied to developing count ...
and disease.Madhuri R, Sudeep SG, Sunila RK, et al. Oral Drug Therapy for Multiple Neglected Tropical Diseases. A Systematic Review. JAMA. 2007;298(16):1911-1924 /ref>


Neglected tropical diseases

Neglected tropical diseases (NTDs) are a group of 13 parasitic and bacterial infections that infect approximately 1.4 billion of the world’s poorest people in sub-Saharan Africa,
Latin America Latin America or * french: Amérique Latine, link=no * ht, Amerik Latin, link=no * pt, América Latina, link=no, name=a, sometimes referred to as LatAm is a large cultural region in the Americas where Romance languages — languages derived f ...
and the Caribbean, and
South East Asia Southeast Asia, also spelled South East Asia and South-East Asia, and also known as Southeastern Asia, South-eastern Asia or SEA, is the geographical south-eastern region of Asia, consisting of the regions that are situated south of mainland ...
. Together, they disable, disfigure, blind, and even kill, causing chronic morbidity that is on par with the “big three” global health threats:
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
,
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, i ...
, and
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
. The Global Network focuses on the seven most common NTDs that together represent 90% of the total NTD disease burden. These seven are: # Ascariasis (
roundworm The nematodes ( or grc-gre, Νηματώδη; la, Nematoda) or roundworms constitute the phylum Nematoda (also called Nemathelminthes), with plant-parasitic nematodes also known as eelworms. They are a diverse animal phylum inhabiting a bro ...
) – 807 million infected #
Trichuriasis Trichuriasis, also known as whipworm infection, is an infection by the parasitic worm ''Trichuris trichiura'' (whipworm). If infection is only with a few worms, there are often no symptoms. In those who are infected with many worms, there may b ...
(
whipworm ''Trichuris trichiura, Trichocephalus trichiuris'' or whipworm, is a parasitic roundworm (a type of helminth) that causes trichuriasis (a type of helminthiasis which is one of the neglected tropical diseases) when it infects a human large intes ...
) – 604 million infected # Hookworm – 576 million infected # Schistosomiasis ( snail fever) – 207 million infected # Lymphatic Filariasis (
elephantiasis Elephantiasis is the enlargement and hardening of limbs or body parts due to tissue swelling. It is characterised by edema, hypertrophy, and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels. It may affect the geni ...
) – 120 million infected #
Trachoma Trachoma is an infectious disease caused by bacterium '' Chlamydia trachomatis''. The infection causes a roughening of the inner surface of the eyelids. This roughening can lead to pain in the eyes, breakdown of the outer surface or cornea of ...
(blinding trachoma) – 84 million infected # Onchocerciasis (
river blindness Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm ''Onchocerca volvulus''. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindne ...
) – 37 million infected


References

{{Authority control Tropical diseases