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The Global Influenza Surveillance and Response System (GISRS) is a global network of laboratories that has for purpose to monitor the spread of
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
with the aim to provide the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
with influenza control information. It was established in 1952 to conduct global influenza surveillance. GISRS is coordinated by WHO and endorsed by national governments. More than two million respiratory specimens are tested by GISRS annually to monitor the spread and evolution of influenza viruses through a network of about 150 laboratories in 114 countries representing 91% of the world's population. GISRS operates FluNet, an online tool used for virological surveillance of influenza.


History

In 1947, the WHO Interim Committee of the United Nations agreed to begin a Global Influenza Programme (GIP) for the study and control of influenza. A major outbreak of influenza in Europe was an immediate concern, as well as the identification of appropriate viruses for a vaccine against the virus strains which might be circulating. The establishment of regional influenza centers began in 1948. Five years after the creation of GIP, the
Global Influenza Surveillance Network National Influenza Centers (also called National Influenza Centres) are institutions which are formally recognized as such by the World Health Organization (WHO).


Composition

As of 2015, GISRS comprised 142 national influenza centers in 115 countries, 6 collaborating centers, 4 essential regulatory laboratories, and 13 H5 reference laboratories.


Efficacy

GISRS is considered an "effective early warning system" for changes in influenza viruses circulating in the global population, which helps mitigate the consequences of a
pandemic A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic disease with a stable number of in ...
and maintain the efficacy of seasonal influenza vaccines.


See also

* Global Influenza Programme * Pandemic Influenza Preparedness Framework


References

{{reflist, 30em Influenza World Health Organization