Glisodin is the
registered trademark of a
nutritional supplement based on two constituents:
*
Cantaloupe extract, which typically contains high quantities of the
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
superoxide dismutase
Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () radical into ordinary molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen ...
(SOD)
*
Gliadin, a wheat
protein designed to protect SOD during the digestive process
Background
As
oxygen
Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements ...
metabolizes in the body, potentially harmful
reactive oxygen species (ROS) are created. The human body implements an
antioxidant defense system to protect against ROS. In the event that these defenses are overpowered by the ROS,
cell damage results (which is a major cause of aging in the body).
Superoxide dismutase
Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () radical into ordinary molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen ...
(SOD) helps to slow the creation of ROS, ultimately playing a key role in the defense against cell damage. However, due to a very fragile
molecular structure, it is particularly prone to damage from stomach acids and digestive
enzymes when taken orally.
Gliadin, which is well known as a
carrier protein for controlled drug release, helps to protect SOD.
Research
A wide range of clinical research has been undertaken to study glisodin's antioxidant capacities. This has extended into a wide range of applications, including protection from ultraviolet radiation, athletic performance, cardiovascular health, ischemia and reperfusion injury.
A group of researchers in France and Germany led by Dr. Claus Muth concluded that glisodin is helpful in protecting against DNA damage caused by hyperbaric oxidation. A 2005 study at Rutgers University also concluded that glisodin is helpful in enhancing athletic performance while minimizing fatigue.
[S. Arent, D. DiFabio, J. Greenwood, J. Pellegrino, C. Williams (2005)]
“Nutritional Supplementation In Male College Soccer Players: Effects On Performance And Oxidative Stress
,” Human Performance Lab, Rutgers University, New Brunswick, NJ.
See also
*
Superoxide dismutase
Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () radical into ordinary molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen ...
*
Oxidative stress
*
Antioxidants
References
{{reflist
External links
Glisodin.org Research Community- clinical research related to SOD/gliadin
Dietary supplements