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George Washington Crile (November 11, 1864 – January 7, 1943) was an
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
surgeon. Crile is now formally recognized as the first surgeon to have succeeded in a direct
blood transfusion Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but mo ...
. He contributed to other procedures, such as neck dissection. Crile designed a small hemostatic forceps which bears his name; the Crile mosquito clamp. He also described a technique for using opioids, regional anesthesia and general anesthesia which is a concept known as balanced anesthesia. He is also known for co-founding the
Cleveland Clinic Cleveland Clinic is a nonprofit American academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921, it runs a 170-acre (69 ha) campus in Cleveland, ...
in 1921.


Early life

Crile was born in Chili, Ohio. He graduated from Ohio Northern University in 1885. In 1887, he received his M.D. from Wooster Medical College which merged to form modern day
Case Western Reserve University School of Medicine Case Western Reserve School of Medicine (CWRU SOM, CaseMed) is the medical school of Case Western Reserve University, a private research university in Cleveland, Ohio. It is the largest biomedical research center in Ohio. History On November ...
. He did further study at Vienna, London and Paris.


Career

He taught at Wooster from 1889 to 1900. He was professor of clinical medicine at Western Reserve University from 1900 to 1911, and was then made professor of surgery. He was chair of surgery at
University Hospitals Case Medical Center University Hospitals Cleveland Medical Center (UH Cleveland Medical Center) is a large not-for-profit academic medical complex in Cleveland, Ohio, United States. University Hospitals Cleveland Medical Center is the main affiliate hospital of Cas ...
from 1910 to 1924, and established its Lakeside Hospital. Crile was responsible for whole blood transfusion, in 1906, and he spurred the use of the new X-ray machines. During the
Spanish–American War , partof = the Philippine Revolution, the decolonization of the Americas, and the Cuban War of Independence , image = Collage infobox for Spanish-American War.jpg , image_size = 300px , caption = (clock ...
, he was made a member of the Medical Reserve Corps and served in
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(1898). He was made an honorable F.R.C.S. (London) in 1913. After America entered
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was List of wars and anthropogenic disasters by death toll, one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, ...
, he became a major in the medical O.T.C., and professional director (1917–18). He served with the British Expeditionary Force (B.E.F.) in France and was senior consultant in surgical research (1918–19). He was made lieutenant-colonel in June 1918, and colonel later in the year. He made important contributions to the study of
blood pressure Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure ...
and of shock in operations. Realizing that any strong emotion, such as fear before operation, produced shock, he attempted to allay dread by psychic suggestion, also endeavouring to prevent the subjective shock which affects the patient, even when under general
anaesthesia Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), a ...
, by first anaesthetizing the operative region with
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for several days, if necessary, before operating. Thus nerve communication between the affected part and the brain was already obstructed when the general anaesthetic was administered. For his work in shockless surgery he received a gold medal from the National Institute of Social Sciences in 1914. When he retired from the Medical School at age 65, Crile went into private practice and worked with those establishing the new
Cleveland Clinic Cleveland Clinic is a nonprofit American academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921, it runs a 170-acre (69 ha) campus in Cleveland, ...
.


Publications

* ''Surgical Shock'' (1897) * ''On the Blood Pressure in Surgery'' (1903) * ''Hemorrhage and Transfusion'' (1909) * ''Surgical Anemia and Resuscitation'' (1914) * ''The Origin and Nature of the Emotions'' (1915) * ''A Mechanistic View of War and Peace'' (1917). * ''Man an Adaptive Mechanism'' (1916) ''The Fallacy of the German State Philosophy'' (1918) * ''The Surgical Treatment of Hypertension'' (1938)


Honors

* * The U.S. Army's Crile General Hospital in Cleveland, Ohio was named in his honor on 21 April 1944. * The
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Crile is also named after him.


Personal life

He married Grace Elizabeth McBride (1876–1948), a sister of
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. His son, George Crile, Jr., was also a surgeon. His grandson George Crile III was a journalist, author, and CBS producer. He died on January 7, 1943, in Cleveland. He is buried in Lake View Cemetery in Cleveland, Ohio.


References


Further reading

* Yentis SM, Hirsch NP, Smith GB editors, ''Anaesthesia and Intensive Care A-Z'', Elsevier Ltd, London, 2000 * *


External links

* (Replacing dead PBS link) * * * {{DEFAULTSORT:Crile, George Washington 1864 births 1943 deaths American surgeons Burials at Lake View Cemetery, Cleveland Case Western Reserve University School of Medicine alumni Cleveland Clinic people Ohio Northern University alumni American expatriates in Austria American expatriates in France American expatriates in the United Kingdom