Guy Thwaites
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Guy Edward Thwaites (born 19 January 1971) is a British professor of
infectious diseases An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
, and director of the Oxford University Clinical Research Unit (OUCRU) in
Ho Chi Minh City , population_density_km2 = 4,292 , population_density_metro_km2 = 697.2 , population_demonym = Saigonese , blank_name = GRP (Nominal) , blank_info = 2019 , blank1_name = – Total , blank1_ ...
in Vietnam. His focus is on severe
bacterial infections Pathogenic bacteria are bacteria that can cause disease. This article focuses on the bacteria that are pathogenic to humans. Most species of bacteria are harmless and are often beneficial but others can cause infectious diseases. The number of t ...
, including
meningitis Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, headache, and neck stiffness. Other symptoms include confusion or ...
and ''
Staphylococcus aureus ''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive ...
'' bloodstream infection, and
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
. He is a former first-class
cricket Cricket is a bat-and-ball game played between two teams of eleven players on a field at the centre of which is a pitch with a wicket at each end, each comprising two bails balanced on three stumps. The batting side scores runs by striki ...
er.


Early life and education

Guy Thwaites was born in
Brighton Brighton () is a seaside resort and one of the two main areas of the City of Brighton and Hove in the county of East Sussex, England. It is located south of London. Archaeological evidence of settlement in the area dates back to the Bronze A ...
in January 1971, to cricketer and physician Ian Thwaites. He was educated at
Eastbourne College Eastbourne College is a co-educational independent school in the British public school tradition, for day and boarding pupils aged 13–18, in the town of Eastbourne on the south coast of England. The College's headmaster is Tom Lawson. Over ...
, before going up to
Girton College, Cambridge Girton College is one of the 31 constituent colleges of the University of Cambridge. The college was established in 1869 by Emily Davies and Barbara Bodichon as the first women's college in Cambridge. In 1948, it was granted full college status ...
. There he completed his pre-clinical years before doing a year in art history. While studying at Cambridge, Thwaites played
first-class cricket First-class cricket, along with List A cricket and Twenty20 cricket, is one of the highest-standard forms of cricket. A first-class match is one of three or more days' scheduled duration between two sides of eleven players each and is officiall ...
for
Cambridge University Cricket Club Cambridge University Cricket Club, first recorded in 1817, is the representative cricket club for students of the University of Cambridge. Depending on the circumstances of each individual match, the club has always been recognised as holding ...
in 1991 and 1992, making four appearances. He scored 68 runs in his four first-class matches at an
average In ordinary language, an average is a single number taken as representative of a list of numbers, usually the sum of the numbers divided by how many numbers are in the list (the arithmetic mean). For example, the average of the numbers 2, 3, 4, 7, ...
of 11.33, with a highest score of 32. Subsequently, he gained admission to study medicine at the
United Medical and Dental Schools of Guy's and St Thomas' Hospitals The United Medical and Dental Schools of Guy's and St Thomas' Hospitals was the name given to the joint medical and dental school formed in London as a result of the merger of Guy's Hospital Medical School, St Thomas's Hospital Medical School an ...
, from where he graduated. While a student, with a friend doing a history PhD, he came across the story of sudor anglicus, the mysterious English sweating sickness of the 15th and 16th centuries. In 1998, five years after the hantavirus outbreak in the US made headlines, and then working at St Thomas' Hospital, he co-authored a paper hypothesising that the mysterious medieval illness was very similar to that in the US and could have been
hantavirus pulmonary syndrome Hantavirus pulmonary syndrome (HPS) is one of two potentially fatal syndromes of zoonotic origin caused by species of hantavirus. These include Black Creek Canal virus (BCCV), New York orthohantavirus (NYV), Monongahela virus (MGLV), ''Sin Nomb ...
. After discovering the grave of Henry Brandon, who he believed had been affected by the illness, he did not propose plans to exhume the body for
DNA analysis Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or ...
.


Career

Thwaites trained in infectious diseases and microbiology at
Brighton University The University of Brighton is a public university based on four campuses in Brighton and Eastbourne on the south coast of England. Its roots can be traced back to 1858 when the Brighton School of Art was opened in the Royal Pavilion. It achieve ...
, the Oxford University Clinical Research Unit (OUCRU) in
Ho Chi Minh City , population_density_km2 = 4,292 , population_density_metro_km2 = 697.2 , population_demonym = Saigonese , blank_name = GRP (Nominal) , blank_info = 2019 , blank1_name = – Total , blank1_ ...
in Vietnam, and the
Hospital for Tropical Diseases The Hospital for Tropical Diseases (HTD) is a specialist tropical disease hospital located in London, United Kingdom. It is part of the University College London Hospitals NHS Foundation Trust and is closely associated with University College Lo ...
, London."Biography for Guy Thwaites"
World Health Organization.
In Vietnam he was a Wellcome Trust Clinician Scientist Fellow and mentored by Nicholas White and
Jeremy Farrar Sir Jeremy James Farrar (born 1 September 1961) is a British medical researcher who has served as director of the Wellcome Trust since 2013 and will serve as chief scientist at the World Health Organization in 2023. He was previously a professo ...
. After more than four years there he returned to London, and two years later joined the
MRC Centre The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together t ...
for Molecular Bacteriology and Infection at Imperial College, where he worked on the bacteria ''Staphylococcus aureus''. He was appointed consultant at Guy's and St Thomas' in 2011. Thwaites was later appointed professor of infectious diseases at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
, and focuses on severe
bacterial infections Pathogenic bacteria are bacteria that can cause disease. This article focuses on the bacteria that are pathogenic to humans. Most species of bacteria are harmless and are often beneficial but others can cause infectious diseases. The number of t ...
, including
meningitis Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, headache, and neck stiffness. Other symptoms include confusion or ...
and ''
Staphylococcus aureus ''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often positive ...
'' bloodstream infection, and
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
. In 2013 he returned to Vietnam as director of the OUCRU, replacing Farrar. In January 2021 in response to the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
he said "vaccination is the only long term strategy".


Honours

In 2018 he was elected a Fellow of the
Academy of Medical Sciences The Academy of Medical Sciences is an organisation established in the UK in 1998. It is one of the four UK National Academies, the others being the British Academy, the Royal Academy of Engineering and the Royal Society. Its mission is to adv ...
in the UK. He holds honorary professorship at the MRC Clinical Trial Units at University College London. In
2021 File:2021 collage V2.png, From top left, clockwise: the James Webb Space Telescope was launched in 2021; Protesters in Yangon, Myanmar following the 2021 Myanmar coup d'état, coup d'état; A civil demonstration against the October–November 2021 ...
he was appointed a
Member of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established o ...
(MBE) for services to public health.


Selected publications

* * * * *


References


External links

*
Thwaites in Google Scholar
{{DEFAULTSORT:Thwaites, Guy 1971 births Living people People from Brighton People educated at Eastbourne College Alumni of Girton College, Cambridge English cricketers Cambridge University cricketers English microbiologists Academics of the University of Oxford Vaccination advocates Members of the Order of the British Empire Fellows of the Academy of Medical Sciences (United Kingdom)