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Margrethe P. Rask (1930 – 12 December 1977), better known as Grethe Rask, was a
Danish Danish may refer to: * Something of, from, or related to the country of Denmark People * A national or citizen of Denmark, also called a "Dane," see Demographics of Denmark * Culture of Denmark * Danish people or Danes, people with a Danish a ...
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
and surgeon in
Zaïre Zaire (, ), officially the Republic of Zaire (french: République du Zaïre, link=no, ), was a Congolese state from 1971 to 1997 in Central Africa that was previously and is now again known as the Democratic Republic of the Congo. Zaire was, ...
(now the
Democratic Republic of the Congo The Democratic Republic of the Congo (french: République démocratique du Congo (RDC), colloquially "La RDC" ), informally Congo-Kinshasa, DR Congo, the DRC, the DROC, or the Congo, and formerly and also colloquially Zaire, is a country in ...
). After setting up her own hospital in the village of Abumombazi in 1972, she transferred to Danish Red Cross Hospital in Kinshasa in 1975. She returned to Denmark in 1977 after developing symptoms of an unknown infectious disease, which was later discovered to be AIDS. Three and a half years later in June 1981 the
Centers for Disease Control The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
recognized AIDS. Rask was one of the first non-Africans (along with
Arvid Noe Arne Vidar Røed (23 July 1946 – 24 April 1976), known in medical literature by the anagram Arvid Darre Noe, was a Norwegian sailor and truck driver who contracted one of the earliest confirmed cases of HIV/AIDS. His was the first confirmed HIV ...
and Robert Rayford) and first non-men who have sex with men known to have died of AIDS-related causes.


Early years and Zaïre (1930–1974)

Born in 1930 in the Danish town of
Thisted Thisted is a town in the municipality of Thisted in the North Denmark Region of Denmark. It has a population of 13,461 (1 January 2022)Zaïre Zaire (, ), officially the Republic of Zaire (french: République du Zaïre, link=no, ), was a Congolese state from 1971 to 1997 in Central Africa that was previously and is now again known as the Democratic Republic of the Congo. Zaire was, ...
for a brief period in 1964, when she was recalled to Europe for training in stomach surgery and tropical illnesses, from 1972 to 1977, first at a small local hospital in the Zairian town of Abumombazi, and then at the chief surgeon at the Danish Red Cross Hospital in Kinshasa starting in 1975. She was likely first exposed to
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
in 1964. Her friend and colleague, Ib Bygbjerg (a physician specializing in
communicable diseases An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dis ...
), wrote in a 1983 letter to ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, ...
'' that "while working as a surgeon under primitive conditions, she
ask Ask is the active verb for a direct question. Ask may also refer to: Places * Ask, Akershus, a village in Gjerdrum municipality, Viken county, Norway * Ask, Buskerud, a village in Ringerike municipality, Viken county, Norway * Ask, Vestland, a ...
must have been heavily exposed to blood and excretions of African patients."


Illness and death (1975–1977)

Rask suffered from symptoms of AIDS starting in late 1974, including
diarrhea Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin w ...
, swollen
lymph nodes A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that inclu ...
, weight loss, and fatigue. Although the symptoms receded temporarily following drug treatments in 1975, they later grew considerably worse. Following a vacation in
South Africa South Africa, officially the Republic of South Africa (RSA), is the Southern Africa, southernmost country in Africa. It is bounded to the south by of coastline that stretch along the Atlantic Ocean, South Atlantic and Indian Oceans; to the ...
in July 1977, she could no longer breathe and relied on bottled
oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as ...
. She flew back to Denmark, where tests at
Copenhagen Copenhagen ( or .; da, København ) is the capital and most populous city of Denmark, with a proper population of around 815.000 in the last quarter of 2022; and some 1.370,000 in the urban area; and the wider Copenhagen metropolitan ar ...
's
Rigshospitalet Rigshospitalet (meaning ''The National'', ''State'' or ''Hospital of the Realm'', but not usually translated) is the largest public and teaching hospital in Copenhagen and the most highly specialised hospital in Denmark. The hospital's main buildi ...
discovered she had contracted a number of opportunistic infections, such as '' Staphylococcus aureus'' (staph infection),
candidiasis Candidiasis is a fungal infection due to any type of '' Candida'' (a type of yeast). When it affects the mouth, in some countries it is commonly called thrush. Signs and symptoms include white patches on the tongue or other areas of the mouth ...
(yeast infection), and ''Pneumocystis jiroveci'' pneumonia (PCP, a fungal infection of the lungs formerly known as ''Pneumocystis carinii'' pneumonia). Tests also showed that Rask had a nearly non-existent
T-cell A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell r ...
count, leading to a severely depressed immune system. At the time, the doctors treating Rask were at a loss to explain her disease progression which, in retrospect, came to be seen as one of the first cases of AIDS recorded outside
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
. After numerous tests and unsuccessful treatments, she eventually returned home to die in her cottage on a fjord in November 1977. She was cared for by Karen Strandby Thomsen. She was called back for more tests in December and returned to the Rigshospitalet in Copenhagen where she remained until she died of AIDS-related ''Pneumocystis jiroveci'' pneumonia on 12 December 1977. In 1984 her blood was tested for HIV in Denmark. The test was negative. In 1987, blood was shipped to the United States, where it was tested with two different systems. Both tests were positive for HIV.


See also

*
Timeline of early AIDS cases HIV/AIDS was recognised as a novel illness in the early 1980s. An AIDS case is classified as "early" if the death occurred before 5 June 1981, when the AIDS epidemic was formally recognized by medical professionals in the United States. Virus o ...


References


Further reading

* ebsite'
Photographs of the real people from Randy Shilts' history of the AIDS crisis "And the Band Played On"
* Shilts, Randy, ''
And the Band Played On ''And the Band Played On: Politics, People, and the AIDS Epidemic'' is a 1987 book by ''San Francisco Chronicle'' journalist Randy Shilts. The book chronicles the discovery and spread of the human immunodeficiency virus (HIV) and acquired immun ...
,'' St. Martin's Press, 1987 {{DEFAULTSORT:Rask, Grethe 1930 births 1977 deaths Danish women physicians AIDS-related deaths in Denmark Danish surgeons Danish LGBT people People from Thisted Deaths from pneumonia in Denmark 20th-century Danish physicians Health in the Democratic Republic of the Congo 20th-century women physicians Date of birth missing 20th-century surgeons 20th-century LGBT people