Grace Pickford
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Grace Evelyn Pickford (March 24, 1902,
Bournemouth, England Bournemouth () is a coastal resort town in the Bournemouth, Christchurch and Poole council area of Dorset, England. At the 2011 census, the town had a population of 183,491, making it the largest town in Dorset. It is situated on the English ...
– January 20, 1986) was an American biologist and endocrinologist, known for "devising ingenious instruments and techniques" and her work on the hematology and endocrinology of
fish Fish are aquatic, craniate, gill-bearing animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish as well as various extinct related groups. Approximately 95% of li ...
es."Grace Pickford"
Biography, Yale University.
"The Grace E. Pickford Collection: 1902-1986"
Hiram College Library (last visited Aug. 16, 2012).


Life and career

Pickford was born in
Bournemouth, England Bournemouth () is a coastal resort town in the Bournemouth, Christchurch and Poole council area of Dorset, England. At the 2011 census, the town had a population of 183,491, making it the largest town in Dorset. It is situated on the English ...
, in 1902. She studied at Newnham College,
Cambridge University , mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Schola ...
, where she was a founding member of the Cambridge University Biological Tea Club.Lawrence B. Slobodkin and Nancy G. Slack
"George Evelyn Hutchinson: 20th Century Ecologist"
''Endeavour'', v.23, n.1 (1999).
She received the equivalent of a B.A., a "National Sciences Tripos, Pt.I", since Cambridge University did not grant B.A.s to women at that time. She then traveled to
South Africa South Africa, officially the Republic of South Africa (RSA), is the southernmost country in Africa. It is bounded to the south by of coastline that stretch along the South Atlantic and Indian Oceans; to the north by the neighbouring countri ...
, collecting and studying earth worms ( oligochaetes). In 1931 she earned her Ph.D. at Yale under
Alexander Petrunkevitch Alexander Ivanovitch Petrunkevitch (Russian: Александр Иванович Петрункевич, December 22, 1875 in Plysky near Kyiv, now Ukraine – March 9, 1964 in New Haven) was an eminent Russian arachnologist of his time. From ...
based on studies of her South African
oligochaete worm Oligochaeta () is a subclass of animals in the phylum Annelida, which is made up of many types of aquatic and terrestrial worms, including all of the various earthworms. Specifically, oligochaetes comprise the terrestrial megadrile earthworms ...
collections. Pickford joined the Bingham Oceanographic Laboratory at Yale in 1931, where she worked for the next forty years. She taught at the assistant professor level from 1934 to 1959, when she was promoted to associate professor, and finally made a full professor of biology at Yale in 1969, retiring shortly thereafter in 1970. Pickford also taught at the women's college Albert Magnus, hired by
Marcella Boveri Marcella Boveri (née O'Grady; October 7, 1863 – October 24, 1950) was an American biologist. She was married to the German biologist Theodor Boveri (1862–1915). Their daughter Margret Boveri (1900–1975) became one of the best-known post-wa ...
. Pickford was a member of various research expeditions, including the 1951 Danish ''Galathea'' expedition, and carried out research in a wide variety of organisms. She is perhaps best known for her foundational work in the field of comparative endocrinology. She did extensive studies of the pituitary hormone
prolactin Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pit ...
, discovering that in killifish prolactin is required to maintain
osmotic balance Osmoregulation is the active regulation of the osmotic pressure of an organism's body fluids, detected by osmoreceptors, to maintain the homeostasis of the organism's water content; that is, it maintains the fluid balance and the concentration of ...
in fresh water; this work was the underpinnings for most research on prolactin in vertebrates.Patricia Stocking Brown
"Early Women Ichthyologists"
''Environmental Biology of Fishes'', v.41, pp.9-30 (1994).
Pickford's 1957 monograph on the topic, "The Physiology of the Pituitary Gland of Fishes", is "considered an early and still enormously useful classic" in the field of comparative endocrinology, the "bible for scientists on the endocrinology of lower vertebrates.""Pickford, Grace Evelyn (1902-1986)", ''Biographical Dictionary of Women in Science'', pp.1020-1021. In the course of this work Pickford developed a number of important techniques still used today in endocrine studies. Similarly, she showed that '' Latimeria'', like sharks, uses
urea Urea, also known as carbamide, is an organic compound with chemical formula . This amide has two amino groups (–) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest amide of carbamic acid. Urea serves an important r ...
to regulate the osmotic pressure of its blood. On the 1951 ''
Galatea Galatea is an ancient Greek name meaning "she who is milk-white". Galatea, Galathea or Gallathea may refer to: In mythology * Galatea (Greek myth), three different mythological figures In the arts * ''Aci, Galatea e Polifemo'', cantata by H ...
'' expedition to the Indo-Malay region, she completed a study of '' Vampyroteuthis'', a deep sea cephalopod that resembles both an octopus and a squid, developing "ingenious" technologies to handle the technical problems of studying in deep seas. Her large collection of water beetles is today stored at Yale's Peabody Museum of Natural History. Pickford was married for a short while (approximately 1931 to 1934) to fellow biologist George Evelyn Hutchinson.


Notable papers

* GE Pickford and JW Atz, "The Physiology of the Pituitary Gland of Fishes" (New York Zoological Society 1957) * FH Epstein, AI Katz, GE Pickford, "Sodium-and potassium-activated adenosine triphosphatase of gills: role in adaptation of teleosts to salt water", ''Science'', 1967 * GE Pickford, JG Phillip, "Prolactin, a factor in promoting survival of hypophysectomized killifish in fresh water", ''Science'' (1959) * Grace E. Pickford, ''A Monograph of the Acanthodriline Earthworms of South Africa'', Cambridge, England: Heffner and Sons, 1937. (Pickford's dissertation.) * Grace E. Pickford, ''Studies on the Digestive Enzymes of Spiders''. New Haven, Conn.: Connecticut Academy of Arts and Sciences, 1942. * Pickford and Bayard H. McConnaughey. ''The Octopus bimaculatus Problem: A Study in Sibling Species''. New Haven, Conn.: Peabody Museum of Natural History, 1949.


Awards

* Distinguished Scientist in Residence,
Hiram College Hiram College ( ) is a private liberal arts college in Hiram, Ohio. It was founded in 1850 as the Western Reserve Eclectic Institute by Amos Sutton Hayden and other members of the Disciples of Christ Church. The college is nonsectarian and coe ...
*
Wilbur Cross Medal The Wilbur Cross Medal, or Wilbur Lucius Cross Medal for Alumni Achievement, is an award by the Yale University Graduate School Alumni Association to recognize "...distinguished achievements in scholarship, teaching, academic administration, and p ...
(Yale), 1981 * The Grace Pickford Medal in Comparative Endocrinology, given by the International Federation of Comparative Endocrinology Societies (IFCES) in her honour, was established in 1980. It is "the highest honour" in comparative endocrinology.York University
"Dr. Suraj Unniappan Chosen for the Grace Pickford Medal"
(press release) (last visited Aug. 16, 2012).


Further reading

* J.N. Ball, "In Memoriam Grace E. Pickford (1902-1986)", ''Gen Comp Endocrinol.'', Jan. 1987, v.65, n.1, pp. 162–165. * Patricia Stocking Brown
"Early Women Ichthyologists"
''Environmental Biology of Fishes'', v.41, pp. 9–30 (1994). * Penelope Jenkin and Anna Bidder, Grace E. Pickford (Obituary), Newnham College, January 1987 * N.G. Slack, "Are research schools necessary? Contrasting models of 20th century research at Yale led by Ross Granville Harrison, Grace E. Pickford and G. Evelyn Hutchinson.", ''J Hist Biol.'', v.36, n.3, pp. 501–529 (Autumn 2003). * "Pickford, Grace Evelyn (1902-1986)", in
Marilyn Bailey Ogilvie Marilyn Bailey Ogilvie (born 1936) is an American historian of science known especially for her work on the history of women in science. She taught at Oklahoma Baptist University before becoming curator of the History of Science Collections and ...
and
Joy Dorothy Harvey Joy Dorothy Harvey (born 1934) is an American historian of science. Life Harvey gained a PhD from Harvard University in 1983. She has been an associate editor of the Darwin Correspondence Project, and written a biography of Clémence Royer, Dar ...
, eds., ''Biographical Dictionary of Women in Science'', pp. 1020–1021.
G. Evelyn Hutchinson Papers
Yale University (letters and other information about his sort marriage and lifelong friendship with Pickford)


Notes

{{DEFAULTSORT:Pickford, Grace Evelyn American biologists American endocrinologists American ichthyologists Women ichthyologists 1902 births 1986 deaths American women biologists American women botanists Women endocrinologists Teuthologists Alumni of Newnham College, Cambridge Yale University faculty Scientists from Bournemouth English emigrants to the United States 20th-century American botanists 20th-century American zoologists 20th-century American women scientists American women academics