The Government Pharmaceutical Organization (GPO) ( th, องค์การเภสัชกรรม; ) is a Thai

state enterprise A state-owned enterprise (SOE) is a government entity which is established or nationalised by the ''national government'' or ''provincial government'' by an executive order or an act of legislation in order to earn profit for the governmen ...

which manufactures pharmaceutical products in Thailand. In 2011, the GPO netted a profit of 1.6 billion

baht The baht (; th, บาท, ; currency sign, sign: ฿; ISO 4217, code: THB) is the official currency of Thailand. It is divided into 100 ''satang'' (, ). The issuance of currency is the responsibility of the Bank of Thailand. Society for Worldw ...

from the sale of pharmaceuticals and medical equipment. As of 2011, the GPO employed 2,812 persons. In 2016, the organization produced drugs at two government-owned factories. GPO makes and sells four categories of products: medicines;

antiretroviral The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multipl ...

s; chemicals/test kits/natural products; and preventive medicines. Besides Thailand, it markets its products in

Nigeria Nigeria ( ), , ig, Naìjíríyà, yo, Nàìjíríà, pcm, Naijá , ff, Naajeeriya, kcg, Naijeriya officially the Federal Republic of Nigeria, is a country in West Africa. It is situated between the Sahel to the north and the Gulf o ...

Ghana Ghana (; tw, Gaana, ee, Gana), officially the Republic of Ghana, is a country in West Africa. It abuts the Gulf of Guinea and the Atlantic Ocean to the south, sharing borders with Ivory Coast in the west, Burkina Faso in the north, and To ...

Bhutan Bhutan (; dz, འབྲུག་ཡུལ་, Druk Yul ), officially the Kingdom of Bhutan,), is a landlocked country in South Asia. It is situated in the Eastern Himalayas, between China in the north and India in the south. A mountainous ...

Somalia Somalia, , Osmanya script: 𐒈𐒝𐒑𐒛𐒐𐒘𐒕𐒖; ar, الصومال, aṣ-Ṣūmāl officially the Federal Republic of SomaliaThe ''Federal Republic of Somalia'' is the country's name per Article 1 of thProvisional Constituti ...

Myanmar Myanmar, ; UK pronunciations: US pronunciations incl. . Note: Wikipedia's IPA conventions require indicating /r/ even in British English although only some British English speakers pronounce r at the end of syllables. As John C. Wells, Joh ...

Sri Lanka Sri Lanka (, ; si, ශ්‍රී ලංකා, Śrī Laṅkā, translit-std=ISO (); ta, இலங்கை, Ilaṅkai, translit-std=ISO ()), formerly known as Ceylon and officially the Democratic Socialist Republic of Sri Lanka, is an ...

Malaysia Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two r ...

Cambodia Cambodia (; also Kampuchea ; km, កម្ពុជា, UNGEGN: ), officially the Kingdom of Cambodia, is a country located in the southern portion of the Indochinese Peninsula in Southeast Asia, spanning an area of , bordered by Thailand t ...

, and

Vietnam Vietnam or Viet Nam ( vi, Việt Nam, ), officially the Socialist Republic of Vietnam,., group="n" is a country in Southeast Asia, at the eastern edge of mainland Southeast Asia, with an area of and population of 96 million, making i ...

. The GPO gives Thailand significant leverage in its price negotiations with foreign drug suppliers. , GPO's chairman is Dr Sopon Mekthon, who took over from Dr Nopporn Cheanklin.

Missions

GPO's mission statement contains four objectives. One of them is to "To maintain price level of pharmaceutical products and medical supplies necessary for the Thai society to ensure people's accessibility." As an example, GPO will produce the antiretroviral drug

efavirenz Efavirenz (EFV), sold under the brand names Sustiva among others, is an antiretroviral medication used to treat and prevent HIV/AIDS. It is generally recommended for use with other antiretrovirals. It may be used for prevention after a needlest ...

after receiving

WHO Who or WHO may refer to: * Who (pronoun), an interrogative or relative pronoun * Who?, one of the Five Ws in journalism * World Health Organization Arts and entertainment Fictional characters * Who, a creature in the Dr. Seuss book '' Horton He ...

approval. GPO's product costs 180

per bottle of thirty 600 mg tablets. The imported version retails for more than 1,000 baht per bottle. GPO will devote 2.5 percent of its manufacturing capacity to make 42 million efavirenz pills in 2018, allowing it to serve export markets as well as domestic. The Philippines alone will order about 300,000 bottles of efavirenz for 51 million baht.

Compulsory licensing

The GPO is permitted to produce efavirenz and two other patented medications by having sought

compulsory licensing A compulsory license provides that the owner of a patent or copyright licenses the use of their rights against payment either set by law or determined through some form of adjudication or arbitration. In essence, under a compulsory license, an ...

(CL) under the provisions of the

WTO The World Trade Organization (WTO) is an intergovernmental organization that regulates and facilitates international trade. With effective cooperation in the United Nations System, governments use the organization to establish, revise, and e ...

agreement on intellectual property, the

Agreement on Trade-Related Aspects of Intellectual Property Rights The Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) is an international legal agreement between all the member nations of the World Trade Organization (WTO). It establishes minimum standards for the regulation by nat ...

(TRIPs). Under a compulsory license, an individual or company seeking to use another's intellectual property can do so—for good reasons—without seeking the rights holder's consent, and pays the rights holder a set fee for the license. This is an exception to the general rule under intellectual property laws that the intellectual property owner enjoys exclusive rights that it may license—or decline to license—to others. In the case of efavirenz, the patent owner,

Merck Merck refers primarily to the German Merck family and three companies founded by the family, including: * the Merck Group, a German chemical, pharmaceutical and life sciences company founded in 1668 ** Merck Serono (known as EMD Serono in the Unite ...

, and the

US Trade Representative The Office of the United States Trade Representative (USTR) is an agency of the Federal government of the United States, United States federal government responsible for developing and promoting Trade policy of the United States, American trade ...

, for years fiercely resisted allowing the GPO to produce the drug.

Products

Sidegra

* Sidegra (

Sildenafil Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. It is taken by ...

) in 50 and 100 mg tablets.

Medical marijuana

GPO produces cannabinoid medicines at its factory in Pathum Thani Province, where it also grows cannabis plants. The organisation is also seeking approval to build a three billion baht, 1,500

rai RAI – Radiotelevisione italiana (; commercially styled as Rai since 2000; known until 1954 as Radio Audizioni Italiane) is the national public broadcasting company of Italy, owned by the Ministry of Economy and Finance. RAI operates many ter ...

(240

hectare The hectare (; SI symbol: ha) is a non-SI metric unit of area equal to a square with 100-metre sides (1 hm2), or 10,000 m2, and is primarily used in the measurement of land. There are 100 hectares in one square kilometre. An acre is a ...

), herb and marijuana facility in

Chonburi Province Chonburi (, , ) is a province of Thailand (''changwat'') located in eastern Thailand. Its capital is also named Chonburi. Neighbouring provinces are (clockwise from north) Chachoengsao, Chanthaburi, and Rayong, while the Bay of Bangkok is to ...

. The GPO led an effort to convince the military government to approve

marijuana Cannabis, also known as marijuana among other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both recreational and entheogenic purposes and in various tra ...

research so that the GPO can market it for medical use. The move would make Thailand the first country in Asia to legalize medical cannabis. Dr. Nopporn Cheanklin, Managing Director of the GPO, said that, "The best strains of

cannabis ''Cannabis'' () is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: ''Cannabis sativa'', '' C. indica'', and '' C. ruderalis''. Alternatively ...

in the world 20 years ago were from Thailand, and now Canada has developed this strain..., we can't claim that ours is the best in the world anymore,...That's why we must develop our strain to...compete with theirs." The government's cabinet of ministers in May 2018 gave the green light to amend the country's drug laws to allow research on medicinal marijuana. The bill is currently being debated in the National Legislative Assembly. Current Thai laws are tough on both the sale and use of marijuana. Possession of cannabis in Thailand could land its owner in jail for up to 15 years as the plant is a category-5 narcotic drug along with psychoactive mushrooms and

kratom ''Mitragyna speciosa'' (commonly known as kratom, an herbal leaf from a tree of the Rubiaceae family, ) is a tropical evergreen tree in the coffee family native to Southeast Asia. It is indigenous to Thailand, Indonesia, Malaysia, Myanmar, and ...

, a psychoactive plant similar to

opiate An opiate, in classical pharmacology, is a substance derived from opium. In more modern usage, the term ''opioid'' is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonis ...

s that is native to Thailand. A researcher at

Chulalongkorn University Chulalongkorn University (CU, th, จุฬาลงกรณ์มหาวิทยาลัย, ), nicknamed Chula ( th, จุฬาฯ), is a public and autonomous research university in Bangkok, Thailand. The university was originally fo ...

has pointed out that Thailand has 200,000

Alzheimer's Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...

patients and 150,000

Parkinson's Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...

patients who could benefit from medical marijuana.

References

External links

GPO Website
{{authority control State enterprises of Thailand Pharmaceutical companies of Thailand