Glycyrrhizinate Beta-glucuronidase
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In
enzymology Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
, a glycyrrhizinate beta-glucuronidase () is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
that
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:glycyrrhizinate + H2O \rightleftharpoons 1,2-beta-D-glucuronosyl-D-glucuronate + glycyrrhetinate Thus, the two substrates of this enzyme are glycyrrhizinate and H2O, whereas its two
products Product may refer to: Business * Product (business), an item that serves as a solution to a specific consumer problem. * Product (project management), a deliverable or set of deliverables that contribute to a business solution Mathematics * Produ ...
are 1,2-beta-D-glucuronosyl-D-glucuronate and glycyrrhetinate. This enzyme belongs to the family of
hydrolase Hydrolase is a class of enzyme that commonly perform as biochemical catalysts that use water to break a chemical bond, which typically results in dividing a larger molecule into smaller molecules. Some common examples of hydrolase enzymes are este ...
s, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ...
of this enzyme class is glycyrrhizinate glucuronosylhydrolase. Other names in common use include glycyrrhizin beta-hydrolase, glycyrrhizin hydrolase, and glycyrrhizinic acid hydrolase.


See also

*
Alpha-glucuronidase ''For beta-glucuronidase, see Beta-glucuronidase'' In enzymology, an alpha-glucuronidase () is an enzyme that catalyzes the chemical reaction :an alpha-D-glucuronoside + H2O \rightleftharpoons an alcohol + D-glucuronate Thus, the two substrate ...
*
Beta-glucuronidase Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. Human β-glucuronidase is a type of glucuronidase (a member of glycosidase Family 2) that catalyzes hydrolysis of β-D-glucur ...
* Glucuronosyl-disulfoglucosamine glucuronidase


References

* EC 3.2.1 Enzymes of unknown structure {{3.2-enzyme-stub