Glycine N-carboxyanhydride is an
organic compound
In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. T ...
with the formula HNCH(CO)
2O. A colorless solid, it is the product of the
phosgenation
Phosgene is the organic chemical compound with the formula COCl2. It is a toxic, colorless gas; in low concentrations, its musty odor resembles that of freshly cut hay or grass. Phosgene is a valued and important industrial building block, esp ...
of
glycine
Glycine (symbol Gly or G; ) is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid ( carbamic acid is unstable), with the chemical formula NH2‐ CH2‐ COOH. Glycine is one of the proteinog ...
.
Glycine N-carboxyanhydride is the simplest member of the
amino acid N-carboxyanhydride
Amino acid ''N''-carboxyanhydrides, also called Leuchs' anhydrides, are a family of heterocyclic organic compounds derived from amino acids. They are white, moisture-reactive solids. They have been evaluated for applications the field of biomate ...
s. It is also the parent of the 2,5-Oxazolidinedione family of heterocycles.
Other derivatives
2,5-Oxazolidinediones can also be prepared from
Schiff base
In organic chemistry, a Schiff base (named after Hugo Schiff) is a compound with the general structure ( = alkyl or aryl, but not hydrogen). They can be considered a sub-class of imines, being either secondary ketimines or secondary aldimine ...
derivatives of amino acids.
See also
*
2,4-Oxazolidinedione, parent ring found in a variety
anticonvulsant drugs.
References
Oxazolidinediones
{{heterocyclic-stub