The
enzyme gluconate dehydratase ()
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
:
D-gluconate
2-dehydro-3-deoxy-
D-gluconate + H
2O
This enzyme belongs to the family of
lyase
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The
systematic name of this enzyme class is
D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include
D-gluconate dehydratase, and
D-gluconate hydro-lyase. This enzyme participates in the
pentose phosphate pathway.
Structural studies
As of late 2007, only one
structure
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as ...
has been solved for this class of enzymes, with the
PDB accession code .
References
*
EC 4.2.1
Enzymes of known structure
{{4.2-enzyme-stub