Glucan 1,4-α-glucosidase (EC 3.2.1.3, glucoamylase, amyloglucosidase', γ-amylase, lysosomal α-glucosidase, acid maltase, exo-1,4-α-glucosidase, glucose amylase, γ-1,4-glucan glucohydrolase, acid maltase, 1,4-α-
D-glucan glucohydrolase) is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
located on the brush border of the small intestine with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
4-α-D-glucan glucohydrolase.
It
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: Hydrolysis of terminal (1→4)-linked α-
D-glucose residues successively from non-reducing ends of the chains with release of β-
D-glucose
Most forms of the enzyme can rapidly hydrolyse 1,6-α-
D-glucosidic bonds when the next bond in the sequence is 1,4. They belong to a variety of different GH families, such as
glycoside hydrolase family 15
In molecular biology, glycoside hydrolase family 15 is a family of glycoside hydrolases.
Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a ...
in fungi,
glycoside hydrolase family 31
In molecular biology, glycoside hydrolase family 31 is a family of glycoside hydrolases.
Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a ...
of human intestine
MGAM, and
glycoside hydrolase family 97
In molecular biology, glycoside hydrolase family 97 is a family of glycoside hydrolases.
Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a ...
of bacterial forms. It was also known as γ-Amylase.
See also
*
Amylase
An amylase () is an enzyme that catalyses the hydrolysis of starch (Latin ') into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of ...
References
External links
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EC 3.2.1