Glisodin is the

registered trademark The registered trademark symbol, , is a typographic symbol that provides notice that the preceding word or symbol is a trademark or service mark that has been registered with a national trademark office. A trademark is a symbol, word, or word ...

of a

nutritional supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order ...

based on two constituents: *

Cantaloupe The cantaloupe, rockmelon (Australia and New Zealand, although cantaloupe is used in some states of Australia), sweet melon, or spanspek (Southern Africa) is a melon that is a variety of the muskmelon species (''Cucumis melo'') from the fami ...

extract, which typically contains high quantities of the

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

superoxide dismutase Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () radical into ordinary molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen me ...

(SOD) *

Gliadin Gliadin (a type of prolamin) is a class of proteins present in wheat and several other cereals within the grass genus ''Triticum''. Gliadins, which are a component of gluten, are essential for giving bread the ability to rise properly during baki ...

, a wheat

protein design Protein design is the rational design of new protein molecules to design novel activity, behavior, or purpose, and to advance basic understanding of protein function. Proteins can be designed from scratch (''de novo'' design) or by making calcula ...

ed to protect SOD during the digestive process

Background

oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as wel ...

metabolizes in the body, potentially harmful

reactive oxygen species In chemistry, reactive oxygen species (ROS) are highly reactive chemicals formed from diatomic oxygen (). Examples of ROS include peroxides, superoxide, hydroxyl radical, singlet oxygen, and alpha-oxygen. The reduction of molecular oxygen () p ...

(ROS) are created. The human body implements an

antioxidant Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. This can lead to polymerization and other chain reactions. They are frequently added to industrial products, such as fuels and lubricant ...

defense system to protect against ROS. In the event that these defenses are overpowered by the ROS,

cell damage Cell damage (also known as cell injury) is a variety of changes of stress that a cell suffers due to external as well as internal environmental changes. Amongst other causes, this can be due to physical, chemical, infectious, biological, nutrition ...

results (which is a major cause of aging in the body).

Superoxide dismutase Superoxide dismutase (SOD, ) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide () radical into ordinary molecular oxygen (O2) and hydrogen peroxide (). Superoxide is produced as a by-product of oxygen me ...

(SOD) helps to slow the creation of ROS, ultimately playing a key role in the defense against cell damage. However, due to a very fragile

molecular structure Molecular geometry is the three-dimensional arrangement of the atoms that constitute a molecule. It includes the general shape of the molecule as well as bond lengths, bond angles, torsional angles and any other geometrical parameters that deter ...

, it is particularly prone to damage from stomach acids and digestive

enzymes Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecule ...

when taken orally.

, which is well known as a

carrier protein A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane ...

for controlled drug release, helps to protect SOD.

Research

A wide range of clinical research has been undertaken to study glisodin's antioxidant capacities. This has extended into a wide range of applications, including protection from ultraviolet radiation, athletic performance, cardiovascular health, ischemia and reperfusion injury. A group of researchers in France and Germany led by Dr. Claus Muth concluded that glisodin is helpful in protecting against DNA damage caused by hyperbaric oxidation. A 2005 study at Rutgers University also concluded that glisodin is helpful in enhancing athletic performance while minimizing fatigue.S. Arent, D. DiFabio, J. Greenwood, J. Pellegrino, C. Williams (2005)
“Nutritional Supplementation In Male College Soccer Players: Effects On Performance And Oxidative Stress
,” Human Performance Lab, Rutgers University, New Brunswick, NJ.

References

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External links

Glisodin.org Research Community
- clinical research related to SOD/gliadin Dietary supplements

Background

Research

See also

References

External links