Gitoformate (
INN, or pentaformylgitoxin, trade name Dynocard) is a
cardiac glycoside, a type of drug that can be used in the treatment of
congestive heart failure and
cardiac arrhythmia (irregular heartbeat). Produced by
Madaus, it is not available in the US, and does not seem to be available in Europe either.
Chemistry
Gitoformate is a derivative of the
glycoside gitoxin, with five of the six free
hydroxyl groups
formylated, one on the
aglycon An aglycone (aglycon or genin) is the compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside
Cardiac glycosides are a class of organic compounds that increase ...
and four on the sugar. Gitoxin, a cardiac glycoside from the
woolly foxglove (''Digitalis lanata''), has an aglycon of the
cardenolide type named gitoxigenin, which is also the aglycon of
lanatoside B, another ''Digitalis lanata'' glycoside.
References
Cardenolides
Formate esters
Tertiary alcohols
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