Germacrene-A Synthase
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The enzyme germacrene-A synthase (EC 4.2.3.23)
catalyzes Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the chemical reaction :(2''E'',6''E'')-farnesyl diphosphate \rightleftharpoons (+)-(''R'')-gemacrene A + diphosphate This enzyme belongs to the family of
lyase In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (2''E'',6''E'')-farnesyl-diphosphate diphosphate-lyase +)-(''R'')-germacrene-A-forming''. Other names in common use include germacrene A synthase, (+)-germacrene A synthase, (+)-(10''R'')-germacrene A synthase, GAS, 2-''trans'',6-''trans''-farnesyl-diphosphate diphosphate-lyase, (germacrene-A-forming).


References

* * * * * EC 4.2.3 Enzymes of unknown structure {{4.2-enzyme-stub