Gerald M. "Jerry" Reaven (July 28, 1928 – February 12, 2018) was an

American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...

endocrinologist Endocrinology (from ''endocrine'' + '' -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events ...

and professor emeritus in medicine at the

Stanford University School of Medicine Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. This ...

Stanford, California Stanford is a census-designated place (CDP) in the northwest corner of Santa Clara County, California, United States. It is the home of Stanford University. The population was 21,150 at the United States Census, 2020, 2020 census. Stanford is ...

, United States. Reaven's work on

insulin resistance Insulin resistance (IR) is a pathological condition in which cell (biology), cells fail to respond normally to the hormone insulin. Insulin is a hormone that facilitates the transport of glucose from blood into cells, thereby reducing blood gluco ...

and

diabetes mellitus Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

with John W. Farquhar goes back at least to 1965. A long-term researcher into

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

, he achieved significant notability with his 1988 Banting Lecture (organized annually by the

American Diabetes Association The American Diabetes Association (ADA) is a United States-based nonprofit that seeks to educate the public about diabetes and to help those affected by it through funding research to manage, cure and prevent diabetes (including type 1 diabetes, ...

in memory of

Frederick Banting Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential. In 1923, Banting and J ...

). In his lecture, he propounded the theory that

central obesity Abdominal obesity, also known as central obesity and truncal obesity, is a condition when excessive visceral fat around the stomach and abdomen has built up to the extent that it is likely to have a negative impact on health. Abdominal obesity has ...

(male-type or apple-shaped obesity), diabetes and

hypertension Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high bl ...

(high blood pressure) have a common cause in

and

impaired glucose tolerance Prediabetes is a component of the metabolic syndrome and is characterized by elevated blood sugar levels that fall below the threshold to diagnose diabetes mellitus. It usually does not cause symptoms but people with prediabetes often have obesit ...

. Initially titled "syndrome X", the constellation of symptoms is now known as the

metabolic syndrome Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndrome ...

and an object of extensive scientific inquiry, especially given that the combination strongly predisposes for

cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...

. Still, Reaven believes that contemporary criteria are arbitrary and that it may not be necessary to define it as a diagnostic entity more than a pathophysiological parameter. He obtained his academic qualifications at the

University of Chicago The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park neighborhood. The University of Chicago is consistently ranked among the b ...

and did his internship there. After research work in Stanford and two years in the U.S.

Army medical corps A medical corps is generally a military branch or officer corps responsible for medical care for serving military personnel. Such officers are typically military physicians. List of medical corps The following organizations are examples of medica ...

he completed his residency at the

University of Michigan , mottoeng = "Arts, Knowledge, Truth" , former_names = Catholepistemiad, or University of Michigania (1817–1821) , budget = $10.3 billion (2021) , endowment = $17 billion (2021)As o ...

. He then took up a

US Public Health Service The United States Public Health Service (USPHS or PHS) is a collection of agencies of the Department of Health and Human Services concerned with public health, containing nine out of the department's twelve operating divisions. The Assistant S ...

research post at Stanford, where he progressed to a full professorship in 1970. He led endocrinology and

gerontology Gerontology ( ) is the study of the social, cultural, psychological, cognitive, and biological aspects of aging. The word was coined by Ilya Ilyich Mechnikov in 1903, from the Greek , ''geron'', "old man" and , ''-logia'', "study of". The fie ...

research.Gerald M. Reaven
curriculum vitae
/ref> Apart from his work at Stanford he was also Senior Vice President for Research for Shaman Pharmaceuticals, Inc. in South San Francisco. He was a member of several research organizations and received numerous prizes for his research achievements. He was co-author of a popular book on Syndrome X and its repercussions on cardiovascular disease.

Footnotes

External links

Interview
- Canadian Association of Cardiac Rehabilitation {{DEFAULTSORT:Reaven, Gerald 1928 births 2018 deaths American endocrinologists Stanford University School of Medicine faculty Pritzker School of Medicine alumni University of Michigan alumni People from Gary, Indiana