George Perry (born April 12, 1953) is a professor of biology and chemistry at the
University of Texas at San Antonio
The University of Texas at San Antonio (UTSA) is a Public university, public research university in San Antonio, Texas. With over 34,000 students across its four campuses spanning 758 acres, UTSA is the Education in San Antonio, largest universi ...
and the former
dean
Dean may refer to:
People
* Dean (given name)
* Dean (surname), a surname of Anglo-Saxon English origin
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* Dean Delannoit, a Belgian singer most known by the mononym Dean
Titles
* ...
of the College of Sciences. Perry is recognized in the field of
Alzheimer's disease research, particularly for his work on
oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal ...
.
Education
Perry received his Bachelor of Arts degree in zoology from
University of California, Santa Barbara
The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a public land-grant research university in Santa Barbara, California with 23,196 undergraduates and 2,983 graduate students enrolled in 2021–2022. It is part of the U ...
. After graduation, he studied at
Scripps Institution of Oceanography,
Hopkins Marine Station Hopkins Marine Station is the marine laboratory of Stanford University. It is located ninety miles south of the university's main campus, in Pacific Grove, California (United States) on the Monterey Peninsula, adjacent to the Monterey Bay Aquarium. ...
of
Stanford University, and the
Marine Biological Laboratory
The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent ...
at Woods Hole; he obtained his Ph.D. from the University of California at San Diego in
Marine Biology under
David Epel David Epel is a researcher at Hopkins Marine Station in Pacific Grove, California, and a Professor (Emeritus) in the Department of Biology at Stanford University.
Epel earned his Ph.D. at University of California Berkeley under Daniel Mazia. He a ...
in 1979. He then received a postdoctoral fellowship in the Department of Cell Biology in the laboratories of
William R. Brinkley, Joseph Bryan and Anthony R. Means at
Baylor College of Medicine
Baylor College of Medicine (BCM) is a medical school and research center in Houston, Texas, within the Texas Medical Center, the world's largest medical center. BCM is composed of four academic components: the School of Medicine, the Graduate S ...
where he laid the foundation for his observations of cytoskeletal abnormalities.
Professional appointments
In 1982, Perry joined the faculty of
Case Western Reserve University, where he holds an adjunct appointment. He is dean of the College of Sciences and professor of biology at the University of Texas at San Antonio. He is distinguished as one of the top Alzheimer's disease researchers with over 1000
publications, one of the top 100 most-cited scientists in Neuroscience & Behavior and one of the top 25 scientists in free radical research. Perry is highly cited (over 82,500 times;H=137;ISI/over 117,000 times;H=170;Google Scholar) and is recognized as an ISI highly cited researcher.
Perry is the current and founding
editor-in-chief
An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies.
The highest-ranking editor of a publication may also be titled editor, managing ...
for the ''
Journal of Alzheimer's Disease'', an international multidisciplinary journal that specialises in
Alzheimer's disease.
He is also a member of the
Alzheimer's Foundation of America
The Alzheimer's Foundation of America (AFA) is an American nonprofit organization based in New York City whose mission is to provide support, services and education to individuals, families and caregivers affected by Alzheimer's disease and relat ...
Medical, Scientific, and Memory Screening Advisory Board.
Perry is fellow of the
American Association for the Advancement of Sciences
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsi ...
,
Sigma Xi
Sigma Xi, The Scientific Research Honor Society () is a highly prestigious, non-profit honor society for scientists and engineers. Sigma Xi was founded at Cornell University by a junior faculty member and a small group of graduate students in 1886 ...
,
Microscopy Society of America, International Engineering and Technology Institute (IETI), Texas Academy of Sciences, past president and past-interim executive director of the Southwestern and Rocky Mountain Division of American Association for the Advancement of Sciences, past chair of the board of the National Organization of Portuguese Americans and past president of the
American Association of Neuropathologists.
Research focus
Perry's research is primarily focused on the mechanism of formation and physiological consequences of the cytopathology of
Alzheimer disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...
.
He has played a key role in elucidating oxidative damage as the initial cytopathological abnormality in
Alzheimer disease
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...
. He is currently working to determine the sequence of events leading to neuronal oxidative damage and the source of the increased
oxygen radicals
In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron.
With some exceptions, these unpaired electrons make radicals highly chemically reactive. Many radicals spon ...
. His current studies focus on two issues: (i) the metabolic basis for the mitochondrial damage restricted to vulnerable
neurons; and (ii) the consequences of RNA oxidation on protein synthesis rate and fidelity.
References
External links
Future Neurology Interview
Journal of Alzheimer's Disease*
Science Watch Top 20 Alzheimer's Researchers PBS InterviewExpress-News Article
{{DEFAULTSORT:Perry, George
Alzheimer's disease researchers
American neuroscientists
Fellows of the American Association for the Advancement of Science
Fellows of the Linnean Society of London
Living people
American people of Portuguese descent
University of Texas at San Antonio faculty
Allan Hancock College alumni
University of California, Santa Barbara alumni
People from Lompoc, California
1953 births
Scripps Institution of Oceanography alumni