Genomic Health
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Genomic Health was a company focusing on genetic research specifically in
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
detection, based out of
Redwood City, California Redwood City is a city on the San Francisco Peninsula in Northern California's Bay Area, approximately south of San Francisco, and northwest of San Jose. Redwood City's history spans its earliest inhabitation by the Ohlone people to being a ...
. The company was acquired by and merged with Exact Sciences Corporation in 2019.


History

Genomic Health, Inc. was founded in 2000 by Randy Scott, who had previously founded and been CEO at
Incyte Incyte is an American multinational pharmaceutical company with headquarters in Wilmington, Delaware, and Morges, Switzerland. The company was created in 2002 through the merger of Incyte Pharmaceuticals, founded in Palo Alto, California in 1991 ...
. He formed the company after a close friend was diagnosed with cancer and had the idea for treatment based on the specific genome of their
tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
. By 2003 Genomic Health had developed Oncotype DX, a genomic assay that quantified the likelihood of
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a r ...
recurrence. This development took the company over three years and to complete and then had to convince skeptics at the time of the validity of genetic testing. In July 2005 Genomic Health filed for an
initial public offering An initial public offering (IPO) or stock launch is a public offering in which shares of a company are sold to institutional investors and usually also to retail (individual) investors. An IPO is typically underwritten by one or more investme ...
to sell up to in common stock. Investors at the time already included Versant Ventures and
Kleiner Perkins Caufield & Byers Kleiner Perkins, formerly Kleiner Perkins Caufield & Byers (KPCB), is an American venture capital firm which specializes in investing in incubation, early stage and growth companies. Since its founding in 1972, the firm has backed entrepreneur ...
. On it was listed on the NASDAQ with the symbol GHDX with the initial share price of for 5016722 shares. Genomic Health also started a subsidiary in 2010,
Invitae Invitae Corp. is a biotechnology company that was created as a subsidiary of Genomic Health in 2010 and then spun-off in 2012. In 2017, Invitae acquired Good Start Genetics and CombiMatrix. In 2020, Invitae announced the acquisition of ArcherDX ...
, with the goal of aggregating multiple genetics tests. Invitae was spun off in 2012. The company expanded with international headquarters in
Geneva , neighboring_municipalities= Carouge, Chêne-Bougeries, Cologny, Lancy, Grand-Saconnex, Pregny-Chambésy, Vernier, Veyrier , website = https://www.geneve.ch/ Geneva ( ; french: Genève ) frp, Genèva ; german: link=no, Genf ; it, Ginevr ...
Switzerland and UK headquarters in
London London is the capital and List of urban areas in the United Kingdom, largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary dow ...
in 2011. In July 2019,
Exact Sciences The exact sciences, sometimes called the exact mathematical sciences, are those sciences "which admit of absolute precision in their results"; especially the mathematical sciences. Examples of the exact sciences are mathematics, optics, astron ...
announced that it was purchasing Genomic Health to increase the variety of medical tests they offer.


See also

*
Human genome The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the ...
* Genetic testing


References


External links

* * {{Authority control Medical genetics Genomics companies Health care companies established in 2000 American companies established in 2000 2000 establishments in California Health care companies based in California Companies based in Redwood City, California Companies formerly listed on the Nasdaq 2005 initial public offerings 2019 mergers and acquisitions