Gadoxetic acid is a
gadolinium-based MRI contrast agent
MRI contrast agents are contrast agents used to improve the visibility of internal body structures in magnetic resonance imaging (MRI). The most commonly used compounds for contrast enhancement are gadolinium-based. Such MRI contrast agents shorten ...
.
Its salt, gadoxetate disodium, is marketed as Primovist in Europe and Eovist in the United States by
Bayer HealthCare Pharmaceuticals
Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceutica ...
.
Medical uses
It is used to increase the T1 signal intensity while imaging the liver lesions such as benign cysts, haemangioma, and liver cancer. It is excreted into bile by active secretion.
Pharmacokinetics
In those with end-stage renal failure, the clearance rate is only 17% with terminal half-life of 12 times longer than the those with normal renal function.
See also
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Gadobenic acid
Gadobenic acid (INN, brand name Multihance) is a complex of gadolinium with the ligand BOPTA. In the form of the methylglucamine salt meglumine gadobenate ( INNm) or gadobenate dimeglumine (USAN), it is used as a gadolinium-based MRI contrast m ...
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Gadopentetic acid
Gadopentetic acid, sold under the brand name Magnevist, is a gadolinium-based MRI contrast agent.
It is usually administered as a salt of a complex of gadolinium with DTPA (''d''iethylene''t''riamine''p''ent''a''cetate) with the chemical formul ...
References
External links
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MRI contrast agents
Organogadolinium compounds
Phenol ethers
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