Probable G-protein coupled receptor 110 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''GPR110''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
This gene encodes a member of the
adhesion-GPCR receptor family.
Family members are characterized by an extended extracellular region with a variable number of
N-terminal
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide. Within a peptide, the amin ...
protein modules coupled to a
TM7
Saccharibacteria, formerly known as ''TM7'',
is a major bacterial lineage. It was discovered through 16S rRNA sequencing .
TM7x from the human oral cavity was cultivated and revealed that TM7x is an extremely small coccus (200-300 nm) a ...
region via a domain known as the GPCR-Autoproteolysis INducing
(GAIN) domain.
References
Further reading
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G protein-coupled receptors
{{transmembranereceptor-stub