Guanine nucleotide-binding protein G(z) subunit alpha is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''GNAZ''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systems. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.
Interactions
GNAZ has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
EYA2
Eyes absent homolog 2 is a protein that in humans is encoded by the ''EYA2'' gene.
Function
This gene encodes a member of the eyes absent (EYA) subfamily of proteins. The encoded protein may be post-translationally modified and may play a rol ...
,
RGS20
Regulator of G-protein signaling 20 is a protein that in humans is encoded by the ''RGS20'' gene.
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are G ...
and
RGS19
Regulator of G-protein signaling 19 is a protein that in humans is encoded by the ''RGS19'' gene.
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and ...
.
References
Further reading
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