GEMIN5
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Gem-associated protein 5 is a protein that in humans is encoded by the ''GEMIN5'' gene.


Function

Gem-associated protein 5 is part of the SMN a large protein complex localized to both the cytoplasm and the
nucleus Nucleus ( : nuclei) is a Latin word for the seed inside a fruit. It most often refers to: *Atomic nucleus, the very dense central region of an atom *Cell nucleus, a central organelle of a eukaryotic cell, containing most of the cell's DNA Nucle ...
that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354),
gem-associated protein 2 Gem-associated protein 2 (GEMIN2), also called survival of motor neuron protein-interacting protein 1 (SIP1), is a protein that in humans is encoded by the ''GEMIN2'' gene. Interactions Gem-associated protein 2 has been shown to interact with D ...
(SIP1; MIM 602595),
GEMIN3 Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3 (GEMIN3), is an enzyme that in humans is encoded by the ''DDX20'' gene. Function DEAD box proteins, characterized by the conserved motif ...
(DDX20; MIM 606168), and
GEMIN4 Gem-associated protein 4 is a protein that in humans is encoded by the ''GEMIN4'' gene. Function The product of this gene is part of the SMN protein complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini b ...
(MIM 606969).


Interactions

GEMIN5 has been shown to
interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with DDX20 and SMN1.


References


Further reading

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