First Databank
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First Databank (FDB) is a major provider of drug and medical device databases that help inform healthcare professionals to make decisions. FDB partners with information system developers to deliver useful medication- and medical device-related information to clinicians, business associates, and patients. FDB is part of Hearst and the Hearst Health network.


History

First Databank was founded in 1977 as a company that published a quarterly magazine of drug prices. They were bought by
Hearst Corporation Hearst Communications, Inc., often referred to simply as Hearst, is an American multinational mass media and business information conglomerate based in Hearst Tower in Midtown Manhattan, New York City. Hearst owns newspapers, magazines, televis ...
in 1980. First Databank then evolved to become a provider of clinical and descriptive drug knowledge that is integrated into healthcare information systems globally. FDB has its headquarters in
San Francisco, California San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17th ...
, and has other offices in
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,
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,
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and
Hyderabad, India Hyderabad ( ; , ) is the capital and largest city of the Indian state of Telangana and the '' de jure'' capital of Andhra Pradesh. It occupies on the Deccan Plateau along the banks of the Musi River, in the northern part of Southern In ...
. The firm's drug databases support pharmacy dispensing, formulary management, drug pricing analysis, claims processing, computerized physician order entry (CPOE), electronic health records (EHR), electronic medical records (EMR), electronic prescribing (e-Prescribing), electronic medication administration records (EMAR), population health and telemedicine/telehealth. Beginning in 2011, First Databank's set of National Drug Codes (NDCs) have been integrated into RxNorm's standard clinical drug vocabulary that includes all medications available on the US market. RxNorm is produced and maintained by the
United States National Library of Medicine The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. Its ...
(NLM). In 2017, FDB acquired Polygot Systems, which simplifies drug information for patients and translates that information into 21 languages. In 2018, FDB partnered with PetIQ to release the first veterinary medication database to provide information on pet medications structured for integration into pharmacy systems. Beginning in 2020, FDB partnered with
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and its
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devices to provide drug information and answer medication questions. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, FDB posted drug data (regarding
remdesivir Remdesivir, sold under the brand name Veklury, Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged. is a broad-spectrum antiviral medication developed by the ...
,
chloroquine Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medi ...
, and
hydroxychloroquine Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, an ...
) and medical device-related coronavirus information to its website. In August 2021, the company announced a partnership with RxRevu to provide integrated decision support tools to improve patient access to care, delivering patient-specific pharmacy benefit information to EHR workflows via direct connections with pharmacy benefit managers. The technology displays accurate, real-time data at the point of prescribing, allowing physicians to find affordable alternatives for medications specific to a patient's health needs and insurance benefits. FDB will offer RxRevu's prescription cost and coverage solution to current and future hospital, health system, and EHR clients.


Operations


FDB MedKnowledge (formerly National Drug Data File Plus)

First Databank's MedKnowledge provides prices, descriptions, and collateral clinical information on drugs approved by the US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA), plus unapproved drugs, commonly used
over-the-counter drug Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs A prescription drug (also prescription medication or prescripti ...
s,
herbal remedies Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. With worldwide research into pharmacology, some herbal medicines have been translated into modern remedie ...
, medical foods and nutritional supplements.


FDB OrderKnowledge (formerly OrderView Med Knowledge Base)

First Databank has developed a drug ordering knowledge base that enables physicians to look up and order drugs. Drug orders are generated based on patient parameters such as age, weight, renal and hepatic impairment, thereby reducing lists of candidate drugs to a minimum. The database is expected to affect the number of
adverse drug reaction An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication. ADRs may occur following a single dose or prolonged administration of a drug or result from the combination of two or more drugs. The meaning of this term ...
s and side effects at facilities that have adopted the electronic order entry systems.


FDB AlertSpace

A web-based software tool that enables institution-specific modification of medication alerts using FDB MedKnowledge clinical modules based on clinician input, localized clinical experience, and other available evidence. The tool allows users to edit or turn off individual alerts, track all alert customizations and create an audit record, and view FDB updates in comparison with the user's own modifications. Users can load the results of their modifications directly into their medication
decision support system A decision support system (DSS) is an information system that supports business or organizational decision-making activities. DSSs serve the management, operations and planning levels of an organization (usually mid and higher management) and h ...
for immediate use in the workflow. The approach follows the normal update process.


FDB Prizm

The FDB Prizm medical device database provides structured, categorized, and normalized information about medical device products that are implanted into patients; hospital and durable medical equipment; and medical supplies. The medical device content comes from a variety of sources such as the FDA, medical device manufacturers, and industry data pools. Also, it encompasses additional information from clinical, operational, and financial attributes and codes. Use of this database within supply chain and other information systems is designed to help decision makers to build and maintain device libraries, identify and document medical devices in case of recalls and adverse events, and group and analyze medical device utilization.


Meducation

Meducation comprises simplified medication instructions and medication regimen calendars using patient-specific information from the electronic health record (EHR). All material is written at a 5th to 8th grade reading level with supporting pictograms in more than 20 languages and is designed to help reduce medication errors and improve medication adherence for all patients.


FDB Targeted Medication Warnings

FDB Targeted Medication Warnings provides patient-specific clinical decision support (CDS) for medications and is integrated directly into the EHR workflow. This content uses lab results, risk scores, and other patient data to suggest clinical guidance that is most relevant to the patient context. The CDS derived from this solution provides specificity for clinical decisions and is linked to the related generic medication alerts which can be filtered out/customized using FDB AlertSpace.


FDB Pet MedKnowledge

FDB Pet MedKnowledge is a comprehensive drug database with veterinary FDA approved medications, allowing veterinarians to access pet medication information whenever and wherever is needed. The service is modeled on the FDB MedKnowledge human medication database.


Litigation

A consumer coalition filed separate suits in a Boston, Massachusetts federal court against drug wholesaler
McKesson Corporation McKesson Corporation is an American company distributing pharmaceuticals and providing health information technology, medical supplies, and care management tools. The company delivers a third of all pharmaceuticals used in North America and emplo ...
and First Databank, accusing the companies of artificially inflating drug prices. The lawsuits say that McKesson and FDB conspired from 2002 through 2005 to set the list prices artificially high. The suit against First DataBank accused it of limiting its survey of wholesalers to a single company, McKesson. First Databank agreed to a settlement, tentatively approved by the federal court, in which it would not pay damages to the plaintiffs, but agreed to reduce
average wholesale price In the United States, the average wholesale price (AWP) is a prescription drug term referring to the average price for medications offered at the wholesale level. The metric was originally intended to convey real pricing information to third-party ...
s (AWPs) listed in its databases by five percent for about 2,033 drugs. McKesson chose to fight the suits. The settlement required First DataBank (FDB) to reduce the AWP mark-up from 1.25 to 1.20 times the Wholesale Acquisition Cost (WAC) for 1,442 NDCs identified in the litigation. FDB set the mark-up at 1.20 for all drugs independent of the litigation on September 26, 2009. The roll back of the WAC-to-AWP spread led to a 4% reduction in their AWP. FDB also stopped publishing AWP data on September 26, 2011, two years after the rollback adjustments were implemented. First DataBank continues to publish non-AWP drug pricing information, including WAC, Direct Price, and suggested wholesale price.


References


External links


Official website
{{DEFAULTSORT:First Databank Publishing companies established in 1982 Hearst Communications publications Pharmaceutical industry Pharmaceuticals policy Publishing companies of the United States Companies based in San Francisco 1982 establishments in the United States