F59 may refer to:
*
EMD F59PH
The EMD F59PH is a four-axle B-B diesel-electric locomotive built by General Motors Electro-Motive Division from 1988 to 1994. A variant, the F59PHI, was produced from 1994 to 2001. The F59PH was originally built for GO Transit commuter oper ...
, a locomotive
* , an armed merchant cruiser of the Royal New Zealand Navy
* , a ''Salisbury''-class frigate of the Royal Navy
* , a Tribal-class destroyer of the Royal Navy
{{Letter-number combination disambiguation