Fructose-2,6-bisphosphate 6-phosphatase
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The enzyme fructose-2,6-bisphosphate 6-phosphatase (EC 3.1.3.54)
catalyzes Catalysis () is the increase in rate of a chemical reaction due to an added substance known as a catalyst (). Catalysts are not consumed by the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recycles quick ...
the reaction :β-D-fructose 2,6-bisphosphate + H2O \rightleftharpoons β-D-fructofuranose 2-phosphate + phosphate This enzyme belongs to the family of
hydrolase In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: :\ce \quad \xrightarrowtext\quad \ce This typically results in dividing a larger molecule into s ...
s, specifically those acting on phosphoric
monoester In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distinct ...
bonds. The
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ...
of this enzyme class is β-D-fructose-2,6-bisphosphate 6-phosphohydrolase. Other names in common use include fructose 2,6-bisphosphate-6-phosphohydrolase, fructose-2,6-bisphosphate 6-phosphohydrolase, and D-fructose-2,6-bisphosphate 6-phosphohydrolase. This enzyme participates in
fructose Fructose (), or fruit sugar, is a Ketose, ketonic monosaccharide, simple sugar found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. It is one of the three dietary monosaccharides, along with glucose and gal ...
and
mannose metabolism Mannose is a sugar with the formula , which sometimes is abbreviated Man. It is one of the monomers of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation ...
.


References

* * EC 3.1.3 Enzymes of unknown structure {{3.1-enzyme-stub