The French–American–British (FAB) classification systems refers to a series of classifications of hematologic diseases. It is based on the presence of
dysmyelopoiesis and the quantification of
myeloblast
The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by G-CSF and other cytokines triggers maturation, differentiation, proliferation a ...
s and
erythroblast
A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus. Almost all vertebrate organisms have hemoglobin-containing cells in their blood, and with the exception of mammals, all of the ...
s.
[
]
It was first produced in 1976.
Types include:
* FAB classification of
acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruisin ...
s: L1–L3 (three subtypes)
* FAB classification of
acute myeloid leukemias: M0–M7 (eight subtypes)
* FAB classification of
myelodysplastic syndromes
Updates continued through at least 1989.
References
Hematologic neoplasms
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