Francis Gilman Blake
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Francis Gilman Blake (22 February 1887–1 February 1952) was a leading American immunologist. He served as dean of the
Yale University School of Medicine The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...
, president of the
American Association of Immunologists The American Association of Immunologists (AAI) is an international scientific society dedicated to furthering the study of immunology. AAI provides its members with a variety of platforms in which to exchange ideas and present the latest immunolo ...
, and physician-in-chief of the
Yale–New Haven Hospital Yale New Haven Hospital (YNHH) is a 1,541-bed hospital located in New Haven, Connecticut. It is owned and operated by the Yale New Haven Health System. YNHH includes the 168-bed Smilow Cancer Hospital at Yale New Haven, the 201-bed Yale New Haven ...
.


Early life and family

Blake was a native of the small
Pennsylvania Pennsylvania (; ( Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, ...
town of Mansfield Valley. His father, a mining engineer, died when he was three years old. He spent much of his childhood in
Massachusetts Massachusetts (Massachusett: ''Muhsachuweesut Massachusett_writing_systems.html" ;"title="nowiki/> məhswatʃəwiːsət.html" ;"title="Massachusett writing systems">məhswatʃəwiːsət">Massachusett writing systems">məhswatʃəwiːsət'' En ...
, where he was an enthusiastic observer of nature; at the age of 15, along with one of his brothers, he submitted an ornithological paper which was published in ''
The Auk ''Ornithology'', formerly ''The Auk'' and ''The Auk: Ornithological Advances'', is a peer-reviewed scientific journal and the official publication of the American Ornithological Society (AOS). It was established in 1884 and is published quarterly. ...
'' in 1902. Paul, John Rodman
"Francis Gilman Blake, 1887-1952"
National Academy of Sciences
He received his A.B. from Dartmouth in 1908, after which he spent a year as a tutor to save enough money to pay for his further education. He then enrolled in
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
, where he received his MD in 1913. While completing his medical internship at
Peter Bent Brigham Peter Bent Brigham (1807–1877) was an American millionaire businessman, restaurateur, real estate trader, and director of the Fitchburg Railroad. He is best known as a philanthropist for his initial endowment of Peter Bent Brigham Hospital an ...
, he met Dorothy P. Dewey, a nurse; they married in 1916 and had three sons."Guide to the Francis Gilman Blake Papers"
Yale University Library The Yale University Library is the library system of Yale University in New Haven, Connecticut. Originating in 1701 with the gift of several dozen books to a new "Collegiate School," the library's collection now contains approximately 14.9 mill ...
During his time at Harvard, he acquired a deep interest in infectious diseases and applied microbiology, reflecting the influence of
Theobald Smith Theobald Smith FRS(For) HFRSE (July 31, 1859 – December 10, 1934) was a pioneering epidemiologist, bacteriologist, pathologist and professor. Smith is widely considered to be America's first internationally-significant medical research scienti ...
, who Blake much admired.


Academic career

Blake joined the faculty of the
University of Minnesota Medical School The University of Minnesota Medical School is the medical school of the University of Minnesota. It is a combination of two campuses situated in Minneapolis and Duluth, Minnesota. The University of Minnesota Medical School is also part of one of ...
in 1917, and the
Rockefeller Institute of Medical Research The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified ...
in 1919."Francis G. Blake"
American Association of Immunologists
Also during this time, he accepted a commission with the
Medical Reserve Corps The Medical Reserve Corps (MRC) is a network in the U.S. of community-based units initiated and established by local organizations aimed to meet the public health needs of their communities. It is sponsored by the Office of the Assistant Secretary ...
, entering as a First Lieutenant in January 1918 and promoting to Captain within three months. He was part of a commission studying the transmission of influenza within army camps, which was a significant problem at the time. He spent 20 months working with Major Russell Cecil at the
Army Medical School Founded by U.S. Army Brigadier General George Miller Sternberg, MD in 1893, the Army Medical School (AMS) was by some reckonings the world's first school of public health and preventive medicine. (The other institution vying for this distinctio ...
, primarily on the production and prevention of bacterial pneumonia in monkeys, the end result being a series of ten papers in the
Journal of Experimental Medicine ''Journal of Experimental Medicine'' is a monthly peer-reviewed medical journal published by Rockefeller University Press that publishes research papers and commentaries on the physiological, pathological, and molecular mechanisms that encompass th ...
. In 1921, he became the John Slade Ely Professor of Medicine at Yale, where he was named Sterling Professor of Medicine in 1927. At the time of his appointment, he was one of the youngest full professors of medicine in Yale's history. He was dean of Yale's medical school from 1940 until 1947. He was the physician-in-chief of Yale-New Haven Hospital for more than thirty years, from 1921 until his death in 1952. He performed significant research in epidemic diseases and some of the first laboratory and clinical tests on penicillin. He was the doctoral advisor of Thomas Francis Jr., who in turn was the advisor of
Jonas Salk Jonas Edward Salk (; born Jonas Salk; October 28, 1914June 23, 1995) was an American virologist and medical researcher who developed one of the first successful polio vaccines. He was born in New York City and attended the City College of New ...
. Blake joined the American Association of Immunologists in 1921 and served as its president from 1934-5, after which he was one of its councillors from 1935-9. He was part of the board of editors of
The Journal of Immunology The ''Journal of Immunology'' is a biweekly peer-reviewed medical journal that publishes basic and clinical studies in all aspects of immunology. Established in 1916, it changed its name to ''Journal of Immunology, Virus Research and Experimental ...
from 1936–42, and an associate editor from 1943-52.


Honors and awards

Blake received numerous honors over the course of his career, including the
Charles V. Chapin Charles Value Chapin (January 17, 1856 – January 31, 1941) was an American pioneer in public health research and practice during the Progressive Era. He was superintendent of health for Providence, Rhode Island between 1884 and 1932. He es ...
Award (1945), U.S. Typhus Commission Medal (1945), and
Medal for Merit The Medal for Merit was, during the period it was awarded, the highest civilian decoration of the United States. It was awarded by the President of the United States to civilians who "distinguished themselves by exceptionally meritorious conduct i ...
(1946). He was made a member of the National Academy of Sciences in 1947 and a fellow in 1948, and became a member of the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
in 1949. His first alma mater, Dartmouth, awarded him an honorary Sc.D. degree in 1936.


Death and named award

In January 1952, Blake took a leave of absence to become the civilian technical director of the U.S. Army's Medical Research and Development Board. He did not hold the position long; at the end of that month he was admitted to Walter Reed Hospital for the treatment of a coronary occlusion, and on 1 February, he died. After his death, an award was established in his honor. The Francis Gilman Blake Award is an annual award to the Yale medical faculty member designated by the graduating class as the most outstanding teacher."The Francis Gilman Blake Award"
Yale J Biol Med. 1952 Jun; 24(6): 577
Some of the notable recipients have included
Hal Blumenfeld Hal Blumenfeld (born March 28, 1962) is a Professor of Neurology, Neuroscience, and Neurosurgery at Yale University. He is an expert on brain mechanisms of consciousness and on altered consciousness in epilepsy. As director of the Yale Clinical Ne ...
, Robert A. Chase, and
Alvan Feinstein Alvan R. Feinstein (December 4, 1925 – October 25, 2001) was an American clinician, researcher and an epidemiologist who made significant impact on clinical investigation, especially on the field of clinical epidemiology that he helped define. H ...
.


References

{{DEFAULTSORT:Blake, Francis Gilman 1887 births 1952 deaths American public health doctors Medal for Merit recipients American medical researchers 20th-century American physicians Yale University faculty Yale Sterling Professors Members of the United States National Academy of Sciences Members of the American Philosophical Society Dartmouth College alumni Harvard Medical School alumni