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Fluvalinate is a synthetic pyrethroid chemical compound contained as an active agent in the products Apistan, Klartan, and Minadox, that is an acaricide (specifically, a miticide), commonly used to control ''Varroa'' mites in honey bee colonies, infestations that constitute a significant disease of such insects. Fluvalinate is a stable, nonvolatile, viscous, heavy oil (technical) soluble in organic solvents. Although the compound may be found in
drones Drone most commonly refers to: * Drone (bee), a male bee, from an unfertilized egg * Unmanned aerial vehicle * Unmanned surface vehicle, watercraft * Unmanned underwater vehicle or underwater drone Drone, drones or The Drones may also refer to: ...
, a study has found
honey Honey is a sweet and viscous substance made by several bees, the best-known of which are honey bees. Honey is made and stored to nourish bee colonies. Bees produce honey by gathering and then refining the sugary secretions of plants (primar ...
samples virtually absent of fluvalinate, on account of its affinity to beeswax.


Stereoisomerism

Fluvalinate is synthesized from racemic valine RS)-valine the synthesis is not diastereoselective. Thus, fluvalinate is a mixture of four stereoisomers, each about 25%. ''Tau''-fluvalinate (τ-fluvalinate) is the trivial name for (2''R'')-fluvalinate. The C atom in the valinate structure is in (''R'')- absolute configuration, while the second chiral atom is a mixture of (''R'')- and (''S'')-configurations:


See also

* Diseases of the honey bee


References


Further reading

*


External links


EPA: Tau-fluvalinate; Reregistration Eligibility Decision for Low Risk Pesticide; Notice of Availability
* * Pyrethroids Chloroarenes Trifluoromethyl compounds Nitriles Phenol ethers Cyanohydrin esters {{antiinfective-drug-stub