Fluprazine (DU-27,716) is a

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...

of the

phenylpiperazine 1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class. List phenylpiperazine derivativesAlpe ...

class. It is a so-called

serenic A serenic, or antiaggressive agent, is a type of drug which reduces the capacity for irritability and aggression. Examples The recreational drug MDMA ("ecstasy") and a variety of related drugs have been described as ''empathogen-entactogens'', or s ...

or anti

aggressive Aggression is overt or covert, often harmful, social interaction with the intention of inflicting damage or other harm upon another individual; although it can be channeled into creative and practical outlets for some. It may occur either reacti ...

agent. It is closely related to several other piperazines, including

eltoprazine Eltoprazine (developmental code name DU-28,853) is a serotonergic drug of the phenylpiperazine class which is described as a serenic or antiaggressive agent. It acts as an agonist of the serotonin 5-HT1A and 5-HT1B receptors and as an antagonis ...

and

batoprazine Batoprazine is a drug of the phenylpiperazine class which has been described as a serenic or antiaggressive agent. It acts as a 5-HT1A receptor, 5-HT1A and 5-HT1B receptor, 5-HT1B receptor agonist. It is closely related to eltoprazine, fluprazine ...

, and

TFMPP 3-Trifluoromethylphenylpiperazine (TFMPP) is a recreational drug Recreational drug use indicates the use of one or more psychoactive drugs to induce an altered state of consciousness either for pleasure or for some other casual purpose or pas ...

, as well as more distantly to the

azapirone Azapirones are a class of drugs used as anxiolytics, antidepressants, and antipsychotics. They are commonly used as add-ons to other antidepressants, such as selective serotonin reuptake inhibitors (SSRIs). Medical uses Azapirones have shown ...

s such as

buspirone Buspirone, sold under the brand name Buspar, among others, is a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder. Benefits support its short-term use. It is taken by mouth, and it may take up to fo ...

. The pharmacology of fluprazine is unknown, but it is likely to act as an

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

at the 5-HT_1A and 5-HT_1B receptors like its sister compound eltoprazine.

References

{{Piperazines meta-Trifluoromethylphenylpiperazines Serotonin receptor agonists Ureas

See also

References