Fluoroestradiol (18F)
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Fluoroestradiol F-18, also known as sup>18F6α-fluoroestradiol and sold under the brand name Cerianna, is a radioactive diagnostic agent indicated for use with
positron emission tomography Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in Metabolism, metabolic processes, and in other physiological activities including bl ...
(PET) imaging. It is an
analog Analog or analogue may refer to: Computing and electronics * Analog signal, in which information is encoded in a continuous variable ** Analog device, an apparatus that operates on analog signals *** Analog electronics, circuits which use analo ...
of
estrogen Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal acti ...
and is used to detect estrogen receptor-positive
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a re ...
lesion A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classifi ...
s.


Chemistry

Chemically, fluoroestradiol F-18 is sup>18F6α-fluoro-3,17β-diol-estratriene-1,3,5(10).


History

Fluoroestradiol F-18 was approved for medical use in the United States in May 2020.


References


External links

* {{DEFAULTSORT:Fluoroestradiol F-18 Secondary alcohols Estradiol Estranes Estrogens Medicinal radiochemistry PET radiotracers Phenols Radiopharmaceuticals Organofluorides Breast cancer