Fisetinidin is an anthocyanidin. It has been obtained from the heartwood of ''

Acacia mearnsii ''Acacia mearnsii'', commonly known as black wattle, late black wattle or green wattle, is a species of flowering plant in the family Fabaceae and is endemic to south-eastern Australia. It is usually an erect tree with smooth bark, bipinnate lea ...

'', from the bark of ''

Rhizophora apiculata Rhizophora apiculata (''R. apiculata'') belongs to the Plantae kingdom under the Rhizophoraceae family. Currently ''R. apiculata'' is distributed throughout Australia (Queensland and Northern Territory), Guam, India, Indonesia, Malaysia, Micrones ...

'' and can also be synthesized. Fisetinidin is very similar in structure to

fisetin Fisetin (7,3′,4′- flavon-3-ol) is a plant flavonol from the flavonoid group of polyphenols. It can be found in many plants, where it serves as a yellow/ochre colouring agent. It is also found in many fruits and vegetables, such as strawberries, ...

, which itself differs in structure from

quercetin Quercetin is a plant flavonol from the flavonoid group of polyphenols. It is found in many fruits, vegetables, leaves, seeds, and grains; capers, red onions, and kale are common foods containing appreciable amounts of it. It has a bitter flavor a ...

only by an additional

hydroxyl In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom. In organic chemistry, alcohols and carboxylic acids contain one or more hydroxy ...

group on the latter. An assay of twenty

flavonoid Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids ...

s showed fisetinidin to be the least effective in inhibition of

CD38 CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in ...

enzyme.

Tannins

Fisetinidin can compose

tannin Tannins (or tannoids) are a class of astringent, polyphenolic biomolecules that bind to and precipitate proteins and various other organic compounds including amino acids and alkaloids. The term ''tannin'' (from Anglo-Norman ''tanner'', ...

s. The polymers are then called

profisetinidin A profisetinidin is a type of condensed tannins formed from leuco-fisetinidin, the leucoanthocyanidin form of fisetinidin. ''Mimosa'' and quebracho tannins are, according to a comparative 13C NMR study of polyflavonoids, found to be predominantly ...

(Porter, 1992).

References

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Tannins

See also

References