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Fikri Alican (2 April 1929 – 19 August 2015) was a Turkish scientist and physician with various contributions to medical science, ranging from
organ transplantation Organ transplantation is a medical procedure in which an organ (anatomy), organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organ ...
to
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
.


Early life and career

Alican was born in
Adapazarı Adapazarı () is a city in northwestern Turkey and the central district of Sakarya Province. The province itself was originally named Adapazarı as well. Adapazarı is a part of the densely populated region of the country known as the Marmara Regi ...
, a city in northwestern
Turkey Turkey ( tr, Türkiye ), officially the Republic of Türkiye ( tr, Türkiye Cumhuriyeti, links=no ), is a list of transcontinental countries, transcontinental country located mainly on the Anatolia, Anatolian Peninsula in Western Asia, with ...
, 150 km east of
Istanbul Istanbul ( , ; tr, İstanbul ), formerly known as Constantinople ( grc-gre, Κωνσταντινούπολις; la, Constantinopolis), is the List of largest cities and towns in Turkey, largest city in Turkey, serving as the country's economic, ...
. He left his hometown after middle school, attending high school and college in Istanbul, where he graduated from
Robert College The American Robert College of Istanbul ( tr, İstanbul Özel Amerikan Robert Lisesi or ), often shortened to Robert, or RC, is a Selective school, highly selective, Independent school, independent, mixed-sex education, co-educational Secondary ...
with a B.S. (1949) and from
Istanbul University , image = Istanbul_University_logo.svg , image_size = 200px , latin_name = Universitas Istanbulensis , motto = tr, Tarihten Geleceğe Bilim Köprüsü , mottoeng = Science Bridge from Past to the Future , established = 1453 1846 1933 ...
with an M.D. (1955). He did his residency at the Istanbul University Medical Center's Clinic of Treatment and Exploratory Surgery, also known as Surgical Clinic #4, headed by Şinasi Hakkı Erel. It is there that he met his future wife, Halide Ihlamur, later Halide Alican, a surgical nurse working at the same clinic. After completing his residency in general surgery at Istanbul University, his growing interest in the field of organ transplantation, then in its heyday, took him to
Jackson, Mississippi Jackson, officially the City of Jackson, is the Capital city, capital of and the List of municipalities in Mississippi, most populous city in the U.S. state of Mississippi. The city is also one of two county seats of Hinds County, Mississippi, ...
, where he joined the
University of Mississippi The University of Mississippi (byname Ole Miss) is a public research university that is located adjacent to Oxford, Mississippi, and has a medical center in Jackson. It is Mississippi's oldest public university and its largest by enrollment. ...
team leading the world in transplantation research, including the first lung transplant (11 June 1963) and the first heart transplant (23 January 1964), under the leadership of James D. Hardy. A few weeks after his arrival there in the summer of 1960, he proposed to Ihlamur, as he always called her, even after she took his name and dropped hers, and they got married in Jackson in November 1960, remaining married for fifty-five years (1960–2015) until his death at age eighty-six. He also obtained a master's degree (M.S., 1962) in physiology at the University of Mississippi, studying with Arthur C. Guyton, while working as a research fellow (soon to become a research associate) in Hardy's department of surgery. Best known for his work in organ transplantation, though with some notable initiatives in physiology as well, Alican later established a successful private practice as a general surgeon. His professional career was divided between medical research in the United States and private practice in Turkey.


Main Contributions

Alican's main contributions came in the 1960s (1960–1971) when he worked at the
University of Mississippi Medical Center University of Mississippi Medical Center (UMMC) is the health sciences campus of the University of Mississippi (Ole Miss) and is located in Jackson, Mississippi, United States. UMMC, also referred to as the Medical Center, is the state's only aca ...
(UMMC) in the pioneering days of laboratory research and clinical studies in organ transplantation. His research focused largely on the lungs and on the liver, though he is also known for his work on intestinal transplantation. He performed the first ever simultaneous bilateral lung transplantation in canines, one of many such operations paving the way for the procedure in humans. His role in the development of surgical techniques in transplantation was complemented by his work in physiology, including transplantation biology in general as well as a particular specialty in the physiology of shock. Relocating to Istanbul in 1971, he held a professorship in surgery at Istanbul University until 1979, turning to private practice upon the institution of legal and regulatory changes barring academic physicians from working outside the university. At the time of his departure from the University of Mississippi, he was an attending surgeon at the university hospital as well as associate director of the transplantation program there. Twenty years later, he became a founding member ("fellow") of th
James D. Hardy Society
established in 1991. He has published extensively both in English and in Turkish. His journal articles, mostly in English, are almost exclusively in the areas of organ transplantation and physiology. His monographs, all in Turkish, are more diverse, ranging from general surgery to organ transplantation to cancer research and the in-depth study of various other diseases. The division mirrors the transformation of his career from
medical research Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientif ...
in the United States to
general surgery General surgery is a surgical specialty that focuses on alimentary canal and abdominal contents including the esophagus, stomach, small intestine, large intestine, liver, pancreas, gallbladder, appendix and bile ducts, and often the thyroid ...
in Turkey. His autobiography (2000/2007) describes that transformation as coming with a natural obstacle to research: the relative scarcity of institutional resources in Turkey at that time. He notes that this not only held back progress in laboratory and clinical studies but also impeded scholarly initiatives inevitably undermined by the inadequacy of academic libraries. The solution he reports having implemented is the creation and maintenance of his own library, complete with a card catalog, populated with entries from leading medical journals acquired with his own funds. Specifically, he reports having maintained personal subscriptions to twenty-two medical journals for over thirty years. He identifies these periodical holdings, supplemented by the selective acquisition of books on an ongoing but less regular schedule, as the main flow of information for the wall-to-wall card catalog in his office where he would personally enter the bibliographic details of each article in every issue. Alican credits this makeshift system for enabling him to publish a combined total of 3,000 pages on top of his output in the United States.


Selected publications


Books


Articles


Notes


References


Gallery

File:Fikri Alican - 1955.05 - age 26 - M.D. graduation.jpg, Fikri Alican (age 26) in May 1955 at graduation from medical school (Istanbul University) File:Fikri Alican - 1955.05 - age 26 - young doctor (graduation year).jpg, Fikri Alican (age 26) in May 1955 as a young doctor fresh out of medical school (Istanbul University) File:Fikri Alican - 1960 summer - age 31 - parents' house.jpg, Fikri Alican (age 31) in the summer of 1960 visiting his parents at their home File:Fikri Alican - 1969.07 - Age 40 - Madrid Organ Transplantation Conference.jpg, Fikri Alican (age 40) in July 1969 at a conference on organ transplantation in Madrid File:Fikri Alican - early 1970s - age early 40s - Istanbul University.jpg, Fikri Alican (age early 40s) in the early 1970s delivering a lecture at Istanbul University File:Fikri Alican - 2005.08 - age 76 - home.jpg, Fikri Alican (age 76) in August 2005 at home File:Fikri Alican - 2006.08 - age 77 - home.jpg, Fikri Alican (age 77) in August 2006 at home File:Fikri Alican - 2006.12 - age 77 - office.jpg, Fikri Alican (age 77) in December 2006 at his office File:Fikri Alican - 2007.06 - age 78 - home.jpg, Fikri Alican (age 78) in June 2007 at home {{DEFAULTSORT:Alican, Fikri Turkish transplant surgeons Cancer researchers Turkish physiologists Turkish medical researchers Robert College alumni Istanbul University alumni University of Mississippi alumni 1929 births 2015 deaths