Fenamic acid is an
organic compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-co ...
, which, especially in its ester form, is called fenamate. serves as a parent structure for several
nonsteroidal anti-inflammatory drug
Non-steroidal anti-inflammatory drugs (NSAID) are members of a Indication (medicine), therapeutic drug class which Analgesic, reduces pain, Anti-inflammatory, decreases inflammation, Antipyretic, decreases fever, and Antithrombotic, prevents bl ...
s (NSAIDs), including
mefenamic acid
Mefenamic acid is a member of the Nonsteroidal anti-inflammatory drug#Anthranilic acid derivatives .28fenamates.29, anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs), and is used to treat mild to m ...
,
tolfenamic acid
Tolfenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of NSAID drugs. Like other members of the class, it is a COX inhibitor and prevents formation of prostaglandins.
It is used in the UK as a treatment for m ...
,
flufenamic acid, and
meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of
anthranilic acid
Anthranilic acid is an aromatic acid with the formula C6H4(NH2)(CO2H) and has a sweetish taste. The molecule consists of a benzene ring, ''ortho''-substituted with a carboxylic acid and an amine. As a result of containing both acidic and basic f ...
.
[Sriram D, Yogeeswari P]
Medicinal Chemistry, 2nd Edition
Pearson Education India, 2010. [
Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone.]
References
{{Prostanoidergics
Anthranilic acids
Nonsteroidal anti-inflammatory drugs