Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an
enzyme that in humans is encoded by the FDPS gene and
catalyzes the
transformation of
dimethylallylpyrophosphate (DMAPP) and
isopentenyl pyrophosphate (IPP) into
farnesylpyrophosphate
Farnesyl pyrophosphate (FPP), also known as farnesyl diphosphate (FDP), is an intermediate in the biosynthesis of terpenes and terpenoids such as Sterol, sterols and Carotenoid, carotenoids. It is also used in the synthesis of CoQ (part of the ele ...
(FPP).
is also involved, as both a
reactant and a
product.
Geranylpyrophosphate
Geranyl pyrophosphate (GPP), also known as geranyl diphosphate (GDP), is the pyrophosphate ester of the terpenoid geraniol. Its salts are colorless. It is a precursor to many natural products.
Occurrence
GPP is an intermediate in the isoprenoid ...
is created in an intermediate step.
See also
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Geranyltranstransferase
In enzymology, a geranyltranstransferase () is an enzyme that catalyzes the chemical reaction
:geranyl diphosphate + isopentenyl diphosphate \rightleftharpoons diphosphate + trans,trans-farnesyl diphosphate
Thus, the two substrates of this enzym ...
References
External links
*
*
EC 2.5.1
{{2.5-enzyme-stub