Formin-like protein 1 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''FMNL1''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.
Interactions
FMNL1 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with
Profilin 1
Profilin-1 is a protein that in humans is encoded by the ''PFN1'' gene.
Function
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in ...
,
PFN2
Profilin-2 is a protein that in humans is encoded by the ''PFN2'' gene.
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to ...
[ and RAC1.][
]
See also
* FMNL2
Formin-like protein 2 is a protein that in humans is encoded by the ''FMNL2'' gene.
Expression
Alternatively spliced transcript variants of the FMNL2 gene encoding different isoforms have been described. The full length FMNL2 (FRL3) protein (10 ...
* FMNL3
Formin-like protein 3 (FMNL3), also known as WW domain-binding protein 3 (WBP-3), is a protein that in humans is encoded by the ''FMNL3'' gene.
Function
The protein encoded by this gene contains a formin homology 2 domain and has high sequence ...
References
Further reading
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