FERb 033 is a
synthetic Synthetic things are composed of multiple parts, often with the implication that they are artificial. In particular, 'synthetic' may refer to:
Science
* Synthetic chemical or compound, produced by the process of chemical synthesis
* Synthetic o ...
,
nonsteroidal estrogen that was
synthesized in 2009 and is used in
scientific research.
It is a
potent and
selective ERβ agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...
(K
i = 7.1 nM,
EC50 = 4.8 nM), with 62-fold selectivity for the ERβ over the
ERα.
See also
*
8β-VE2
8β-VE2, or 8β-vinylestradiol, also known as 8β-vinylestra-1,3,5(10)-triene-3β,17β-diol, is a synthetic estrogen featuring an estradiol core. It is a highly potent and selective agonist of the ERβ that is used in scientific research to st ...
*
Diarylpropionitrile
*
ERB-196
*
Erteberel
*
Prinaberel
*
WAY-166818
*
WAY-200070
*
WAY-214156
References
Chloroarenes
Fluoroarenes
Aldoximes
Selective ERβ agonists
Synthetic estrogens
Phenols
Biphenyls
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