Caspase-10 (, ''FLICE2, Mch4'', ''CASP-10'', ''ICE-like apoptotic protease 4'', ''apoptotic protease Mch-4'', ''FAS-associated death domain protein interleukin-1beta-converting enzyme 2'') is an

enzyme An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...

. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...

: Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Leu-Gln-Thr-Asp!Gly Caspase-10 is an initiator

caspase Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death. They are named caspases due to their specific cyste ...

, as are caspase-2 ( EC 3.4.22.55), caspase-8 ( EC 3.4.22.61) and caspase-9 ( EC 3.4.22.62).

References

External links

* {{Portal bar, Biology, border=no EC 3.4.22