Family with sequence similarity 177 member A1 (FAM177A1) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''FAM177A1''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
, previously known as C14orf24. The other member of this family is
FAM177B.
Function
FAM177A1 has been linked to immune system regulation and to neurogenesis.
Interactions
IntActreports physical interactions between FAM117A1 and these other human proteins:
*
Aquaporin-6
*
Caspase 6
Caspase-6 is an enzyme that in humans is encoded by the ''CASP6'' gene.
''CASP6'' orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians ...
*
DPM3
*
ELOVL4
Elongation of very long chain fatty acids protein 4 is a protein that in humans is encoded by the ''ELOVL4'' gene.
ELOVL4 is a member of a large family of fatty acid elongases (ELO), that catalyzes the rate-limiting step in the elongation of long ...
*
FATE1
* JAGN1
*
LAMP2
Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins.
The protein encoded by this gene is a ...
*
PBX3
Pre-B-cell leukemia transcription factor 3 is a protein that in humans is encoded by the ''PBX3'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ...
*
SGPL1
Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the ''SGPL1'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generati ...
*
SH3GLB1
Endophilin-B1 is a protein that in humans is encoded by the ''SH3GLB1'' gene. Endophilin-B1 belongs to the Bin/Amphiphysin/Rvs167 (BAR) family of proteins and plays a critical role in mitochondrial fission and fusion, as well as in autophagy and ...
* TMX2
References
External links
FAM177A1 Research Fund (for FAM177A1 Associated Disease)
{{Protein-stub