Enzo Emanuele (born June 10, 1977) is an

Italian Italian(s) may refer to: * Anything of, from, or related to the people of Italy over the centuries ** Italians, an ethnic group or simply a citizen of the Italian Republic or Italian Kingdom ** Italian language, a Romance language *** Regional Ita ...

clinical pathologist Clinical pathology is a medical specialty that is concerned with the diagnosis of disease based on the Medical laboratory, laboratory analysis of bodily fluids, such as blood, urine, and tissue homogenates or extracts using the tools of clinic ...

known for his

interdisciplinary Interdisciplinarity or interdisciplinary studies involves the combination of multiple academic disciplines into one activity (e.g., a research project). It draws knowledge from several other fields like sociology, anthropology, psychology, ec ...

research in the field of biological psychology. He has studied the biochemical basis of romantic

interpersonal attraction Interpersonal attraction as a part of social psychology is the study of the attraction between people which leads to the development of platonic or romantic relationships. It is distinct from perceptions such as physical attractiveness, and in ...

and identified the

neurotrophin Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth fact ...

nerve growth factor Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was ...

(NGF) as a key biochemical mediator of falling in

love Love encompasses a range of strong and positive emotional and mental states, from the most sublime virtue or good habit, the deepest Interpersonal relationship, interpersonal affection, to the simplest pleasure. An example of this range of ...

. The implications of this research have been criticized in the popular press. In 2008, his genetic research, which showed an association between

serotonin Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and va ...

and

dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% o ...

receptor gene polymorphisms and certain love traits, was awarded with the International Zdenek Klein

Award An award, sometimes called a distinction, is something given to a recipient as a token of recognition of excellence in a certain field. When the token is a medal, ribbon or other item designed for wearing, it is known as a decoration. An awar ...

for Human

Ethology Ethology is the scientific study of animal behaviour, usually with a focus on behaviour under natural conditions, and viewing behaviour as an evolutionarily adaptive trait. Behaviourism as a term also describes the scientific and objecti ...

from the

Charles University in Prague ) , image_name = Carolinum_Logo.svg , image_size = 200px , established = , type = Public, Ancient , budget = 8.9 billion CZK , rector = Milena Králíčková , faculty = 4,057 , administrative_staff = 4,026 , students = 51,438 , under ...

Czech Republic The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The ...

. Emanuele is also known for his studies on

biomarkers In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pa ...

of atherosclerosis. On October 3, 2009, Enzo Emanuele was awarded by the

Society for the Study of

Atherosclerosis Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheromatous plaque. At onset there are usually no s ...

(SISA),

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Section, with the Giovanni Galli

Prize A prize is an award to be given to a person or a group of people (such as sporting teams and organizations) to recognize and reward their actions and achievements.

for his scientific contributions in the field of cardiovascular biomarkers. He graduated as MD from the

University of Pavia The University of Pavia ( it, Università degli Studi di Pavia, UNIPV or ''Università di Pavia''; la, Alma Ticinensis Universitas) is a university located in Pavia, Lombardy, Italy. There was evidence of teaching as early as 1361, making it one ...

Pavia Pavia (, , , ; la, Ticinum; Medieval Latin: ) is a town and comune of south-western Lombardy in northern Italy, south of Milan on the lower Ticino river near its confluence with the Po. It has a population of c. 73,086. The city was the ...

Italy Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical ...

in 2002. Emanuele is Associate Editor of the journal ''Atherosclerosis''. He is also member of the Editorial Board of the ''Journal of Special Education and Rehabilitation''.

Contributions to science

* Identification of sRAGE, the soluble form of the receptor for advanced glycation endproducts, as related to

atherosclerosis Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheromatous plaque. At onset there are usually no s ...

dementia Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affe ...

, and

longevity The word " longevity" is sometimes used as a synonym for " life expectancy" in demography. However, the term ''longevity'' is sometimes meant to refer only to especially long-lived members of a population, whereas ''life expectancy'' is always ...

. * Identification of the

(NGF) as a biochemical mediator of falling in

in humans. * Genetic dissection of human

mating In biology, mating is the pairing of either opposite- sex or hermaphroditic organisms for the purposes of sexual reproduction. ''Fertilization'' is the fusion of two gametes. ''Copulation'' is the union of the sex organs of two sexually reprod ...

system and love styles. * Identification of

biochemical markers A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be ...

autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...

. *

Genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar work ...

of sporadic

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...

. * Identification of

related to

aggressive behaviour Aggression is overt or covert, often harmful, social interaction with the intention of inflicting damage or other harm upon another individual; although it can be channeled into creative and practical outlets for some. It may occur either reacti ...

domestic animals This page gives a list of domesticated animals, also including a list of animals which are or may be currently undergoing the process of domestication and animals that have an extensive relationship with humans beyond simple predation. This includ ...

. * Role of

and

omega-3 fatty acids Omega−3 fatty acids, also called Omega-3 oils, ω−3 fatty acids or ''n''−3 fatty acids, are polyunsaturated fatty acids (PUFAs) characterized by the presence of a double bond, three atoms away from the terminal methyl group in their chem ...

in experimental

neuroeconomics Neuroeconomics is an interdisciplinary field that seeks to explain human decision-making, the ability to process multiple alternatives and to follow through on a plan of action. It studies how economic behavior can shape our understanding of t ...

. * Researchers led by Dr Enzo Emanuele have traced the genetic component of

cellulite Cellulite is the herniation of subcutaneous fat within fibrous connective tissue that manifests as skin dimpling and nodularity, often on the pelvic region (specifically the buttocks), lower limbs, and abdomen. Cellulite occurs in most postpube ...

to particular polymorphisms in the

angiotensin converting enzyme Angiotensin-converting enzyme (), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstr ...

(

ACE An ace is a playing card, die or domino with a single pip. In the standard French deck, an ace has a single suit symbol (a heart, diamond, spade, or club) located in the middle of the card, sometimes large and decorated, especially in the c ...

) and hypoxia-inducible factor 1A (

HIF1a Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the ''HIF1A'' gene. The Nobel Prize in Physiology or Medicine 2019 was awarde ...

) genes.

References

External links

The European Atherosclerosis Society

Associate Editors of Atherosclerosis

{{DEFAULTSORT:Emanuele, Enzo Italian medical researchers Living people 1977 births Italian pathologists People from Robbio