Eduard Hitzig (6 February 1838 – 20 August 1907) was a German

neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...

and

neuropsychiatrist Neuropsychiatry or Organic Psychiatry is a branch of medicine that deals with psychiatry as it relates to neurology, in an effort to understand and attribute behavior to the interaction of neurobiology and social psychology factors. Within neurop ...

Jewish Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...

ancestryAndrew P. Wickens, ''A History of the Brain: From Stone Age Surgery to Modern Neuroscience'', Psychology Press (2014), p. 226 born in

Berlin Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constitue ...

. He studied medicine at the Universities of

and

Würzburg Würzburg (; Main-Franconian: ) is a city in the region of Franconia in the north of the German state of Bavaria. Würzburg is the administrative seat of the ''Regierungsbezirk'' Lower Franconia. It spans the banks of the Main River. Würzburg is ...

under the instruction of famous men such as

Emil Du Bois-Reymond Emil Heinrich du Bois-Reymond (7 November 181826 December 1896) was a German physician and physiologist, the co-discoverer of nerve action potential, and the developer of experimental electrophysiology. Life Du Bois-Reymond was born in Berlin a ...

(1818–1896),

Rudolf Virchow Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder ...

(1821–1902), Moritz Heinrich Romberg (1795–1873), and

Karl Friedrich Otto Westphal Karl Friedrich Otto Westphal (23 March 1833, in Berlin – 27 January 1890, in Kreuzlingen) was a German psychiatrist from Berlin. He was the son of Otto Carl Friedrich Westphal (1800–1879) and Karoline Friederike Heine and the father of Alexa ...

(1833–1890). He received his doctorate in 1862 and subsequently worked in Berlin and Würzburg. In 1875, he became director of the

Burghölzli The ''Psychiatrische Universitätsklinik Zürich'' (Psychiatric University Hospital Zürich) is a psychiatric hospital in Switzerland. As a research hospital, it is associated with the University of Zürich. It is also called Burghölzli, after th ...

asylum, as well as professor of

psychiatry Psychiatry is the medical specialty devoted to the diagnosis, prevention, and treatment of mental disorders. These include various maladaptations related to mood, behaviour, cognition, and perceptions. See glossary of psychiatry. Initial psych ...

at the

University of Zurich The University of Zürich (UZH, german: Universität Zürich) is a public research university located in the city of Zürich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 f ...

. In 1885, Hitzig became a professor at the

University of Halle Martin Luther University of Halle-Wittenberg (german: Martin-Luther-Universität Halle-Wittenberg), also referred to as MLU, is a public, research-oriented university in the cities of Halle and Wittenberg and the largest and oldest university i ...

where he remained until his retirement in 1903. Hitzig is remembered for his work concerning the interaction between electric current and the

brain A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a v ...

. In 1870, Hitzig, assisted by

anatomist Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...

Gustav Fritsch Gustav Theodor Fritsch (5 March 1838 – 12 June 1927) was a German anatomist, anthropologist, traveller and physiologist from Cottbus. Fritsch studied natural science and medicine in Berlin, Breslau and Heidelberg. In 1874 he became an ass ...

(1837–1927), applied electricity via a thin probe to the exposed

cerebral cortex The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of ...

of a dog without

anesthesia Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), ...

. They performed these studies at the home of Fritsch because the

University of Berlin Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative o ...

would not allow such experimentation in their laboratories. What Hitzig and Fritsch had discovered is that electrical stimulation of different areas of the

cerebrum The cerebrum, telencephalon or endbrain is the largest part of the brain containing the cerebral cortex (of the two cerebral hemispheres), as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In ...

caused involuntary muscular contractions of specific parts of the dog's body. They identified the brain's "motor strip", a vertical strip of brain tissue on the

in the back of the

frontal lobe The frontal lobe is the largest of the four major lobes of the brain in mammals, and is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is parted from the parietal lobe by a groove betwe ...

, which controls different muscles in the body. In 1870, Hitzig published his findings in an essay called ''Ueber die elektrische Erregbarkeit des Grosshirns'' (On the Electrical Excitability of the Cerebrum). This experimentation was considered the first time anyone had done any localized study regarding the brain and electric current. However this was not the first time Hitzig had experienced the interaction between the brain and electricity; earlier in his career as a physician working with the Prussian Army, he experimented on wounded soldiers whose

skull The skull is a bone protective cavity for the brain. The skull is composed of four types of bone i.e., cranial bones, facial bones, ear ossicles and hyoid bone. However two parts are more prominent: the cranium and the mandible. In humans, the ...

s were fractured by bullets. Hitzig noticed that applying a small electric current to the brains of these soldiers caused involuntary muscular movement. Hitzig and Fritsch's work opened the door to further localized testing of the brain by many others including Scottish neurologist,

David Ferrier Sir David Ferrier FRS (13 January 1843 – 19 March 1928) was a pioneering Scottish neurologist and psychologist. Ferrier conducted experiments on the brains of animals such as monkeys and in 1881 became the first scientist to be prosecuted ...

References

* Mind as Mosaic (The Robot in the Machine), Bruce H. Hinrichs * ''Parts of this article are based on a translation of an article from the German Wikipedia.''

External links

* {{DEFAULTSORT:Hitzig, Eduard 1839 births 1907 deaths 19th-century German Jews German neurologists German psychiatrists University of Halle faculty Physicians from Berlin People associated with the University of Zurich University of Zurich faculty