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Evan Vere Shute (21 October 1905 – 1978) F.R.C.S.C. was a Canadian
obstetrician Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surgi ...
, poet and writer best known for advocating vitamin E therapy to treat
cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, h ...
and many other diseases. His studies were not controlled and his results were not confirmed by other medical researchers.


Biography

Shute was born in
Bruce County Bruce County is a county in Southwestern Ontario, Canada comprising eight lower-tier municipalities and with a 2016 population of 66,491. It is named for James Bruce, 8th Earl of Elgin and 12th Earl of Kincardine, sixth Governor General of the P ...
and was raised on a farm near Lion's Head with his younger brothers Wilfred and Wallace.Baker, Michael; Neary, Hilary Bates. (2005). ''100 Fascinating Londoners''. James Lorimer & Company. p. 76. His parents were Richard James Shute and Elizabeth Jane Treadgold.''The Canadian Who's Who, Volume 12''
University of Toronto Press, 1972. p. 1019
Shute and his brothers became medical doctors. Evan and Wilfred graduated from the
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
. He obtained his B.A. in 1924 and M.B. in 1927. He married Marian Roberta, they had five children. He was Research Assistant of Obstetrics and Gynaecology at
University of Western Ontario The University of Western Ontario (UWO), also known as Western University or Western, is a Public university, public research university in London, Ontario, London, Ontario, Canada. The main campus is located on of land, surrounded by resident ...
(1933–1939). Shute served as President for the Canadian Society for Study of Fertility and was an associate member of the
Royal Society of Medicine The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers ...
. Shute authored children's stories, poetry and verse under the pen name Vere Jameson.


Vitamin E therapy

In the 1930s, Shute and his brother Wilfred became advocates of Vitamin E therapy. In 1946, Shute, Wilfred and Albert Vogelsang reported that larges doses of vitamin E are beneficial to treat four major types of heart disease. However, these claims were not confirmed by the medical community. In 1948, Shute and Wilfred founded the Shute Medical Clinic (also known as the Shute Institute) in
London, Ontario London (pronounced ) is a city in southwestern Ontario, Canada, along the Quebec City–Windsor Corridor. The city had a population of 422,324 according to the 2021 Canadian census. London is at the confluence of the Thames River, approximate ...
at 10 Grand Avenue where they treated patients with Vitamin E therapy. In 1949, the Shute Institute began to publish the journal, ''The Summary''. This was published because Shute had difficultly publishing his research in North American medical journals. Shute and Wilfred recommended their patients to take 400–600 International Units (IU) of vitamin E per day; later they advocated 800 IU per day or over. They warned individuals with high blood pressure not to take any vitamin E supplements before their blood pressure was controlled.Marshall, Charles W. (1986)
''Vitamins and Minerals: Help or Harm?''
George F. Stickley Company. p. 76. pp. 133-134
Shute stated that vitamin E could be used to treat heart disease as he had used it to treat his mother's
angina Angina, also known as angina pectoris, is chest pain or pressure, usually caused by ischemia, insufficient blood flow to the Cardiac muscle, heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typical ...
attacks. In 1954, Shute and his brother received widespread media coverage as the ''
Time Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, to ...
'' magazine published a supportive article on their vitamin E therapy.Armstrong, David. (1991). ''The Great American Medicine Show: Being an Illustrated History of Hucksters, Healers, Health Evangelists, and Heroes from Plymouth Rock to the Present''. Prentice Hall. pp. 239-240. Shute lectured on the subject but after clinical trials did not support his claims he was barred from addressing major medical conferences. During this time, many dangerous and unproven health claims were being promoted about vitamin E therapy causing the
United States Postal Service The United States Postal Service (USPS), also known as the Post Office, U.S. Mail, or Postal Service, is an independent agency of the executive branch of the United States federal government responsible for providing postal service in the U ...
to ban vitamin E literature with unproven health claims from the mail. Shute received support from alternative health advocates such as
Adelle Davis Adelle Davis (25 February 1904 – 31 May 1974) was an American writer and nutritionist, considered "the most famous nutritionist in the early to mid-20th century." She was an advocate for improved health through better nutrition. She wrote an e ...
and
J. I. Rodale Jerome Irving Rodale (; August 16, 1898 – June 8, 1971) was a publisher, editor, and author who founded Rodale, Inc. in Emmaus, Pennsylvania, and The Rodale Institute, formerly the Soil Health Foundation. Rodale was an early advocate of sustai ...
. Rodale visited Shute's clinic and was impressed so began taking 1, 200 IU of vitamin E every day (24 times the 1990 Recommended Dietary Allowance). Rodale wrote that taking vitamin E in large doses would prevent him from having a heart attack, however, he died from a heart attack, age 72. In 1969, Shute authored the book ''The Heart and Vitamin E'', published by his Shute Foundation for Medical Research. The book recommended large doses of vitamin E for the prevention and treatment of many diseases and disorders including angina,
gangrene Gangrene is a type of tissue death caused by a lack of blood supply. Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. The feet and hands are most commonly affected. If the ga ...
, heart disease,
nephritis Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules. It is one of several different types of nephropathy. Types * Glomerulonephritis is inflammation of th ...
,
stroke A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functionin ...
,
varicose vein Varicose veins, also known as varicoses, are a medical condition in which superficial veins become enlarged and twisted. These veins typically develop in the legs, just under the skin. Varicose veins usually cause few symptoms. However, some indi ...
s and to heal wounds and scars.Herbert, Victor. (1981). ''Vitamins and "Health" Foods: The Great American Hustle''. George F. Stickley Company. pp. 98-99. By 1972, the sales of vitamin E in the United States had increased by 500%. The same year, Shute told ''
Newsweek ''Newsweek'' is an American weekly online news magazine co-owned 50 percent each by Dev Pragad, its president and CEO, and Johnathan Davis (businessman), Johnathan Davis, who has no operational role at ''Newsweek''. Founded as a weekly print m ...
'' that "It provides better circulation and enhances the power of the muscles. Almost nothing in the body wouldn't be improved by a large intake of vitamin E."
Linus Pauling Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific top ...
wrote approvingly of Shute's vitamin E therapy. In 1987, Pauling wrote that "there is no doubt that Wilfrid Shute and Evan Shute were convinced that vitamin E is the most important substance in the world. I confess to having the same feeling about vitamin C."


Criticism

Shute's health claims about vitamin E have never been scientifically demonstrated. Drs. Robert E. Olson, Robert Hodges and Terence Anderson who examined Shute's claims found that vitamin E therapy has no benefit for angina from well-designed studies published between 1946 and 1972. They noted that Shute's case studies were poorly-designed and that all available trials on the subject have been negative. Dr. Hodges in a 1973 review noted that none of the Shute brothers studies were controlled and concluded that "massive doses of vitamin E are useless in the prevention or treatment of coronary heart disease."
Victor Herbert Victor August Herbert (February 1, 1859 – May 26, 1924) was an American composer, cellist and conductor of English and Irish ancestry and German training. Although Herbert enjoyed important careers as a cello soloist and conductor, he is be ...
also stated that none of Shute's health claims about vitamin E were based on well designed experimental studies and quoted Shute as opposing controlled trials as unethical. In 1978, nutritionist Fredrick J. Stare commented:


Creationism

Shute was a Christian and
old earth creationist Old Earth creationism (OEC) is an umbrella of theological views encompassing certain varieties of creationism which may or can include day-age creationism, gap creationism, progressive creationism, and sometimes theistic evolutionism. Broadly spe ...
who authored the book ''Flaws in the Theory of Evolution'', in 1966. Shute aimed for a wide audience and did not cite any Biblical passages in the book but made frequent references to the "Creator" and "Grand Designer". Tom McIver has noted that Shute "dismisses, the standard biological evidence for evolution, including embryological evidence, vestigial organs, serology (biochemistry), and biogeography. He argues that parasite life-cycles, mimicry, interdependence of species, instinct, social insects, and many other examples of extraordinary adaptations refute evolution." The
National Center for Science Education The National Center for Science Education (NCSE) is a not-for-profit membership organization in the United States whose stated mission is to educate the press and the public on the scientific and educational aspects of controversies surrounding t ...
has negatively reviewed the book for misrepresenting evidence for evolution from the
fossil record A fossil (from Classical Latin , ) is any preserved remains, impression, or trace of any once-living thing from a past geological age. Examples include bones, shells, exoskeletons, stone imprints of animals or microbes, objects preserved in ...
and ignoring basic biological facts regarding
species In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...
. The book was criticized for making non-scientific arguments for a Grand Designer."Anti-Evolution Books Chosen in 1998"
National Center for Science Education The National Center for Science Education (NCSE) is a not-for-profit membership organization in the United States whose stated mission is to educate the press and the public on the scientific and educational aspects of controversies surrounding t ...
. Retrieved 28 October 2021.


Selected publications

As Vere Jameson *''Moths After Midnight'' (1945) *''The Sultan Of Jobat'' (1947) *''Omar From Nishapur'' (1948) *''Where The Heron Stands'' (1949) *''Sky Painter'' (1951) *''The Trumpets Fade'' (1973) As Evan Shute
''The Influence of Vitamin E on Vascular Disease''
(with Arthur B. Vogelsang, Floyd R. Skelton and Wilfred E. Shute, 1948)
''Therapeutic Uses of Vitamin E''
(with Wilfrid E. Shute, 1953)
''Your Heart and Vitamin E''
(with Wilfrid E. Shute, 1956) *''Common Questions On Vitamin E and Their Answers'' (1961) *''Flaws in the Theory of Evolution'' (1966) *''The Heart and Vitamin E'' (1963, 1969) *''The Vitamin E Story: The Medical Memoirs of Evan Shute'' (with James C. M. Shute, 1985)


See also

*
Orthomolecular medicine Orthomolecular medicine is a form of alternative medicine that aims to maintain human health through nutritional supplementation. The concept builds on the idea of an optimal nutritional environment in the body and suggests that diseases reflect ...


References

{{DEFAULTSORT:Shute, Evan 1905 births 1978 deaths 20th-century Canadian physicians 20th-century Canadian male writers 20th-century Canadian non-fiction writers 20th-century Canadian novelists 20th-century Canadian poets Alternative cancer treatment advocates Canadian medical writers Canadian obstetricians Christian Old Earth creationists Intelligent design advocates Orthomolecular medicine advocates People from Bruce County Pseudoscientific diet advocates University of Toronto alumni University of Western Ontario faculty Vitamin researchers Writers from Ontario