Euphrosyne Kastamonitissa was a
Byzantine
The Byzantine Empire, also referred to as the Eastern Roman Empire or Byzantium, was the continuation of the Roman Empire primarily in its eastern provinces during Late Antiquity and the Middle Ages, when its capital city was Constantin ...
noblewoman of the
Kastamonites family, a wife of
Andronikos Doukas Angelos (a cousin of the ruling
Komnenos dynasty
Komnenos ( gr, Κομνηνός; Latinized Comnenus; plural Komnenoi or Comneni (Κομνηνοί, )) was a Byzantine Greek noble family who ruled the Byzantine Empire from 1081 to 1185, and later, as the Grand Komnenoi (Μεγαλοκομνην� ...
) and mother of the two future
Byzantine emperors
This is a list of the Byzantine emperors from the foundation of Constantinople in 330 AD, which marks the conventional start of the Byzantine Empire, Eastern Roman Empire, to Fall of Constantinople, its fall to the Ottoman Empire in 1453 AD. On ...
from the
Angelos
The House of Angelos (; gr, Ἄγγελος), feminine form Angelina (), plural Angeloi (), was a Byzantine Greek noble lineage which rose to prominence through the marriage of its founder, Constantine Angelos, with Theodora Komnene, the youn ...
family:
Isaac II Angelos
Isaac II Angelos or Angelus ( grc-gre, Ἰσαάκιος Κομνηνός Ἄγγελος, ; September 1156 – January 1204) was Byzantine Emperor from 1185 to 1195, and again from 1203 to 1204.
His father Andronikos Doukas Angelos was ...
and
Alexios III Angelos
Alexios III Angelos ( gkm, Ἀλέξιος Κομνηνός Ἄγγελος, Alexios Komnēnos Angelos; 1211), Latinized as Alexius III Angelus, was Byzantine Emperor from March 1195 to 17/18 July 1203. He reigned under the name Alexios Komnen ...
.
Under Manuel I Komnenos
Euphrosyne and Andronikos married . Together they had eight children, six sons and two daughters. However in 1179/80 Andronikos attempted to annul his legal marriage with Euphrosyne, so to marry another woman that he had fallen in love with. Andronikos' matrimonial plans failed thanks to the intervention of Emperor
Manuel I Komnenos
Manuel I Komnenos ( el, Μανουήλ Κομνηνός, translit=Manouíl Komnenos, translit-std=ISO; 28 November 1118 – 2